Protein Alignment KLK11 and CG34458

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 85/284 - (29%)
• Similarity: 133/284 - (46%)
• Gaps: 53/284 - (18%)

Human    35 ILQLILLALATGL------VGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
            :::|.:|.||...      |..|:|||.|....|...|.|.:|....|..||.:||:...::|||
  Fly     7 LVKLSILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAA 71

Human    94 HC--------LKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESF 150
            ||        :|..|.       :.|||:.|....:::::|:| .::|.|.::
  Fly    72 HCTMGQNPGQMKAIVG-------TNDLSAGNGQTFNIAQFIIH-PRYNPQSQD------------ 116

Human   151 PHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL--SSRCVTAGTSCLISGWGSTSSPQLR 213
                           .|:.|:|::|||.:..||:.:.|  |.....|.|..:|||:|:.:. .|:
  Fly   117 ---------------FDMSLIKLSSPVPMGGAVQTIQLADSDSNYAADTMAMISGFGAINQ-NLQ 165

Human   214 LPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQ 278
            ||:.|:.|.:.:.....|.:.....:||.||||....|...||||||||||..:..|.|::|||.
  Fly   166 LPNRLKFAQVQLWSRDYCNSQNIPGLTDRMVCAGHPSGQVSSCQGDSGGPLTVDGKLFGVVSWGF 230

Human   279 DPCAITRKPGVYTKVCKYVDWIQE 302
            . |....:|.:||.|.....||::
  Fly   231 G-CGAKGRPAMYTYVGALRSWIKQ 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/256 (30%)
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	78/259 (30%)