Protein Alignment KLK11 and CG34436

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_001097954.1
• Gene: CG34436 / 5740743
• FlyBaseID: FBgn0085465
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 66/271 - (24%)
• Similarity: 108/271 - (39%)
• Gaps: 81/271 - (29%)

Human    64 SQPWQAALF--EKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYI 126
            |:||.|.:.  .||   |...||...:::|:|.                       |:.:..|.|
  Fly    40 SRPWMALVLLPNKT---CSGALIHKYFVITSAS-----------------------CVFNQERAI 78

Human   127 VHLGQHNLQKEEGCEQTRT---ATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL 188
            |.|||.::::|.....:..   ...::.|..:..|  |.:|  ||.|:::.:.|.....:||:
  Fly    79 VRLGQLSIKQEHIVSYSSDDYHVQSAYIHRFYEKS--NFEH--DIALLELQNDVLYKAHIRPI-- 137

Human   189 SSRCVTAGTSCLIS---------GWGSTSSPQLRLPHTLRCANITIIEH---QKCENA---YPGN 238
               |:....|.:.:         .||....      :.|..|..:.|:|   .|||||   ||.|
  Fly   138 ---CLWLDKSDIDTQMFKRYETFRWGIDEK------YILPAAKTSKIKHISQVKCENAFKLYPQN 193

Human   239 ITDTMVCASVQEGGKDSCQGDSGGPLV--------CNQSLQGIISWGQDPCAITRKPGVYTKVCK 295
               :.:||..:  .|..|. ::|.||.        ...:|.||.|:|:.      :..:||.|.|
  Fly   194 ---SHICAGYK--NKSKCV-ETGSPLFKKIRYYTKIRYTLFGIQSYGES------RTCLYTDVTK 246

Human   296 YVDWIQETMKN 306
            |:|||...::|
  Fly   247 YIDWIMGVIQN 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	63/263 (24%)
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:473915	64/264 (24%)