Protein Alignment KLK11 and alphaTry

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 82/281 - (29%)
• Similarity: 132/281 - (46%)
• Gaps: 48/281 - (17%)

Human    38 LILLALATGLVGG----------ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92
            :|||:.....:||          :.||:.|......|.|||.:|.......||.::.:...::||
  Fly     5 VILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTA 69

Human    93 AHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP-HPGFN 156
            ||||:...:............||...::.:|                         ||. |.|:|
  Fly    70 AHCLQSVSASVLQVRAGSTYWSSGGVVAKVS-------------------------SFKNHEGYN 109

Human   157 -NSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRC 220
             |::.     |||.:::::|.:|.:.:::.::|::.....|.|..:||||:.||....:|..|:.
  Fly   110 ANTMV-----NDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVSGWGTQSSGSSSIPSQLQY 169

Human   221 ANITIIEHQKCENA---YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCA 282
            .|:.|:...:|.::   |...|.:||:||:.  .|||:||||||||||....|.|::|||.. ||
  Fly   170 VNVNIVSQSQCASSTYGYGSQIRNTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CA 231

Human   283 ITRKPGVYTKVCKYVDWIQET 303
            .:..||||..|.....|:..|
  Fly   232 YSNYPGVYADVAVLRSWVVST 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/251 (30%)
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	75/251 (30%)