Protein Alignment KLK11 and CG11313

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_651821.3
• Gene: CG11313 / 43646
• FlyBaseID: FBgn0039798
• Length: 370
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 129/298 - (43%)
• Gaps: 73/298 - (24%)

Human    47 LVGGE---TRIIKG-------------FECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHC 95
            :.||:   .:|.||             .|.:||..       ::.|..|..:||..|:::|||||
  Fly   106 ICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDG-------QQLRTYCAGSLINNRYVVTAAHC 163

Human    96 LKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGC-------EQTRTATESFP-H 152
                ||..:... ..|:|         .|..|.||:||......|       |..:.|.|... |
  Fly   164 ----VSAATRAR-KGDVS---------FRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIH 214

Human   153 PGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSS----RCVTAGTSCLISGWGST----SS 209
            ..|...|    ..|||.|:::|..|:.:.::||:.|.|    :...:|.:..::|||.|    ||
  Fly   215 ESFGTRL----FWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESS 275

Human   210 P-QLRLPHTLRCANITIIEHQKCENAYPGNIT--DTMVCASVQEGGKDSCQGDSGGPLVCNQS-- 269
            | :::|       .:|.:|...|...|...:.  |:.:||..:..| |||.|||||||:....
  Fly   276 PVKMKL-------RVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRG-DSCDGDSGGPLMAFHEGV 332

Human   270 --LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMK 305
              |.||:|:|.: |.....|.|||.|..|..||.:.::
  Fly   333 WVLGGIVSFGLN-CGSRFWPAVYTNVLSYETWITQNIR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	82/282 (29%)
CG11313	NP_651821.3	CLIP	24..78	CDD:463440
		Tryp_SPc	116..367	CDD:238113	84/284 (30%)