Protein Alignment KLK11 and CG5246

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_650603.1
• Gene: CG5246 / 42072
• FlyBaseID: FBgn0038484
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 82/274 - (29%)
• Similarity: 126/274 - (45%)
• Gaps: 57/274 - (20%)

Human    46 GLVGGETRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVS 109
            |.|..|||:|.|.:......|:|.::... ...:||.::|||:|:||||||:: |.
  Fly    34 GHVKPETRVIGGVDSPTGFAPYQVSIMNTFGEHVCGGSIIAPQWILTAAHCME-WP--------- 88

Human   110 PDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPG---------FNNSLPNKDHR 165
                     :.:|.  ||                 |.|..:..||         .:.|.....:.
  Fly    89 ---------IQYLK--IV-----------------TGTVDYTRPGAEYLVDGSKIHCSHDKPAYH 125

Human   166 NDIMLVKMASPVSITWAVRPLTLSSR--CVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEH 228
            |||.|:..|.|:......:|:.|:|:  ....|....::|||||.: ..|....|:..::..|:|
  Fly   126 NDIALIHTAKPIVYDDLTQPIKLASKGSLPKVGDKLTLTGWGSTKT-WGRYSTQLQKIDLNYIDH 189

Human   229 QKCENAYPGN--ITDTMVCASVQEGGKDSCQGDSGGPLV-CNQSLQGIISWGQDPCAITRKPGVY 290
            ..|::.....  :::..||...|| |:.||.|||||||| .||:|.|:::|| :.||| ..|.|:
  Fly   190 DNCQSRVRNANWLSEGHVCTFTQE-GEGSCHGDSGGPLVDANQTLVGVVNWG-EACAI-GYPDVF 251

Human   291 TKVCKYVDWIQETM 304
            ..|..|.|||::.|
  Fly   252 GSVAYYHDWIEQMM 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/261 (29%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	76/262 (29%)