Protein Alignment KLK11 and CG4053

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 76/286 - (26%)
• Similarity: 132/286 - (46%)
• Gaps: 49/286 - (17%)

Human    33 MRILQLILLALATGLVGG---------ETRIIKGFECKPHSQPWQAAL--FEKTRLLCGATLIAP 86
            :.::.|:||..:..:..|         :.||:.|.|.:....|:|.::  ..||. :|...::..
  Fly     5 LSLIWLLLLGTSIDVTRGKRLDNRKLLDNRIVGGQEAEDGVAPYQVSIQTIWKTH-ICSGVILNE 68

Human    87 RWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP 151
            :|:|||.||                  :.::.:..| |.||..   |.:.|.|  ||....|:..
  Fly    69 QWILTAGHC------------------ALDFSIEDL-RIIVGT---NDRLEPG--QTLFPDEALV 109

Human   152 HPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGS--TSSPQLRL 214
            |..::  :|.. :.|||.|:.:...:......:.:.||.....||::..::|||:  :|.|.::.
  Fly   110 HCLYD--IPYV-YNNDIALIHVNESIIFNDRTQIVELSREQPPAGSTVTLTGWGAPESSYPTVQY 171

Human   215 PHTLRCANITIIEHQKCENA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWG 277
            ..||   |:|||.|::|...  :...|....:|...:| |:.:|.|||||||:....|.|:::||
  Fly   172 LQTL---NLTIIAHEECRERWDFHDGIDIGHICTFTRE-GEGACSGDSGGPLMWEGKLVGLVNWG 232

Human   278 QDPCAITRKPGVYTKVCKYVDWIQET 303
            : .|.: ..|.:|.....|.|||:.|
  Fly   233 R-ACGV-GMPDMYANTVYYQDWIRRT 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	69/252 (27%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	70/254 (28%)