Protein Alignment KLK11 and Sb

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 81/280 - (28%)
• Similarity: 119/280 - (42%)
• Gaps: 58/280 - (20%)

Human    51 ETRIIKGFECKPHSQPWQAAL-------FEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHV 108
            ||||:.|........|||.::       |..|. .||..||...|:.||.||:
  Fly   541 ETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTH-RCGGALINENWIATAGHCV------------ 592

Human   109 SPDLSSS-------NYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRN 166
             .||..|       .|..||:...:.::             .|...:...||.::    ...:..
  Fly   593 -DDLLISQIRIRVGEYDFSHVQEQLPYI-------------ERGVAKKVVHPKYS----FLTYEY 639

Human   167 DIMLVKMASPVSITWAVRPLTL-SSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQK 230
            |:.|||:..|:.....|.|:.| .:..:..|.:..::|||..|... .||..|:..::.|:.:..
  Fly   640 DLALVKLEQPLEFAPHVSPICLPETDSLLIGMNATVTGWGRLSEGG-TLPSVLQEVSVPIVSNDN 703

Human   231 CENAY--PGN---ITDTMVCASVQEGGKDSCQGDSGGPLVCNQS-----LQGIISWGQDPCAITR 285
            |::.:  .|.   |.|..:||..:.||:|||||||||||.....     |.||||||.. ||...
  Fly   704 CKSMFMRAGRQEFIPDIFLCAGYETGGQDSCQGDSGGPLQAKSQDGRFFLAGIISWGIG-CAEAN 767

Human   286 KPGVYTKVCKYVDWIQETMK 305
            .|||.|::.|:..||.|.::
  Fly   768 LPGVCTRISKFTPWILEHVR 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	76/271 (28%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	77/273 (28%)