Protein Alignment KLK11 and CG12951

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 83/295 - (28%)
• Similarity: 134/295 - (45%)
• Gaps: 65/295 - (22%)

Human    31 QAMRILQLILLALATGLVG----GETRIIKGFECKPHSQPWQAAL--FEKTRLLCGATLIAPRWL 89
            |.:.:..:::||:.|  ||    ..:|::.|.:......|:..:|  ::.:. .||.::|:..::
  Fly     5 QDLSLSLIVILAVTT--VGQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSH-SCGGSIISKHFV 66

Human    90 LTAAHCLKPWVSLTSPTHVSP-DLSSSNYCLSHLSRY------IVHLGQHNLQKEEGCEQTRTAT 147
            :|||||          |:..| |..|..:.::::|..      |..:.||
  Fly    67 MTAAHC----------TNGRPADTLSIQFGVTNISAMGPNVVGIKKIIQH--------------- 106

Human   148 ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITW-AVRPLTLSSRCVT-----AGTSCLISGWG- 205
            |.|.        |.:.:.|||.|:.:..|..... :|.|:.|.:....     ||...::.|||
  Fly   107 EDFD--------PTRQNANDISLLMVEEPFEFDGVSVAPVELPALAFAVPQSDAGVEGVLIGWGL 163

Human   206 --STSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTM--VCASVQEGGKDSCQGDSGGPLVC 266
              :..|.|    .||:..::.|...::|.:.:.|. ||..  :|..|.||||..|.|||||||:.
  Fly   164 NDTYGSVQ----DTLQEVSLKIYSDEECTSRHNGQ-TDPKYHICGGVDEGGKGQCSGDSGGPLIY 223

Human   267 NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQ 301
            |....||:||...||.:...||||.||.:|||||:
  Fly   224 NGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/266 (28%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	76/268 (28%)