Protein Alignment KLK11 and Sp7

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_649734.2
• Gene: Sp7 / 40918
• FlyBaseID: FBgn0037515
• Length: 391
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 84/304 - (27%)
• Similarity: 136/304 - (44%)
• Gaps: 97/304 - (31%)

Human    59 ECKPHSQP---------------WQAALFE------KTRLLCGATLIAPRWLLTAAHCLKPWVSL 102
            :|.|||..               |. ||.|      :..|.||.:||..|::||||||:
  Fly   127 KCGPHSFSNKVYNGNDTAIDEFNWM-ALLEYVDNRGRRELSCGGSLINNRYVLTAAHCV------ 184

Human   103 TSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGC--------------EQTRTATESFPHP 153
                     :.:....:.||:  .|.||:::..|:..|              ||...      ||
  Fly   185 ---------IGAVETEVGHLT--TVRLGEYDTSKDVDCIDDICNQPILQLGIEQATV------HP 232

Human   154 GFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL---SSR-CVTAGTSCLISGWG-------ST 207
            .::.:  ||:..:||.|:::..||.:...::|:.|   |:| .:..|...::||||       ||
  Fly   233 QYDPA--NKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTARKST 295

Human   208 SSPQLRLPHTLRCANITIIEHQKCENAYPG---NITDTMVCASVQEGG---KDSCQGDSGGPLV- 265
            ...:|.||         :.:|..|...:..   ::..:.:|.    ||   :|||.|||||||:
  Fly   296 IKQRLDLP---------VNDHDYCARKFATRNIHLISSQLCV----GGEFYRDSCDGDSGGPLMR 347

Human   266 --CNQS--LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMK 305
              .:|:  .:|::|:| :.|.:...|||||:|..|:|||.||::
  Fly   348 RGFDQAWYQEGVVSFG-NRCGLEGWPGVYTRVADYMDWIVETIR 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	80/297 (27%)
Sp7	NP_649734.2	CLIP	31..84	CDD:463440
		Tryp_SPc	137..388	CDD:238113	78/290 (27%)