Protein Alignment KLK11 and CG4613

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 308
• Identity: 97/308 - (31%)
• Similarity: 145/308 - (47%)
• Gaps: 57/308 - (18%)

Human    12 SSGRGLTAAKEPGARSSPLQ-----AMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAAL 71
            :|..|.|:.....:...||:     |.|:.:   .|..|..|....||:.|.:.:.:..||.|.:
  Fly    93 ASSLGSTSLSSSASPVFPLEGGGAKAFRVNR---CASCTCGVPNVNRIVGGTQVRTNKYPWIAQI 154

Human    72 FEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQK 136
            ...|.|.||.|||..|::||||||:.           ..|:...:..|..|.|...|||
  Fly   155 IRGTFLFCGGTLINDRYVLTAAHCVH-----------GMDMRGVSVRLLQLDRSSTHLG------ 202

Human   137 EEGCEQTRTATESFPHPGFNN-SLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT--AGTS 198
                 .||:...:..|.|::. ||.     :||.|:::..|:.:...:||..|.|..:.  ....
  Fly   203 -----VTRSVAFAHAHVGYDPVSLV-----HDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQK 257

Human   199 CLISGW------GSTSSPQLRLPHTLRCANITIIEHQKCE-NAYPGNITDTMVCAS-VQEGGKDS 255
            .:::||      |||||       .|:...:.||.:.:|. .:|...|.|||:||. |:.||:|:
  Fly   258 AIVAGWGLSQEGGSTSS-------VLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDA 315

Human   256 CQGDSGGPLVCNQ---SLQGIISWGQDPCAITRKPGVYTKVCKYVDWI 300
            |||||||||:...   .|.|::|:|.. ||....|||||:|.:|::||
  Fly   316 CQGDSGGPLIVRDRIFRLAGVVSFGYG-CAKPDAPGVYTRVSRYLEWI 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	85/260 (33%)
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	85/260 (33%)