Protein Alignment KLK11 and CG10663

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_001097592.1
• Gene: CG10663 / 39421
• FlyBaseID: FBgn0036287
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 103/340 - (30%)
• Similarity: 144/340 - (42%)
• Gaps: 78/340 - (22%)

Human     8 RDWKSSGRGLTAAKE--PGARSSPLQAMRILQ------------LIL------------LALATG 46
            :.|..:....|.|.|  ||: .||..|||.:|            .|:            |.|:.|
  Fly   427 QQWLQTQFQKTPAFETRPGS-GSPANAMRRMQSEQPEVSMNDLNYIMTGKGYRGPEYTPLKLSCG 490

Human    47 LVGGET---------RIIKGFECKPHSQPWQAALFEKTR-LLCGATLIAPRWLLTAAHCLKPWVS 101
            :|...|         :||.|...:....|||.|:..:.: ..||.|||||||:||||||::..:
  Fly   491 IVRSGTGRRSMSNMLKIIGGRAARKGEWPWQVAILNRFKEAFCGGTLIAPRWVLTAAHCVRKVL- 554

Human   102 LTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRN 166
                                    .|.:|:|||..|:|.|......:|:.||.|:....:    :
  Fly   555 ------------------------FVRIGEHNLNYEDGTEIQLRVMKSYTHPNFDKRTVD----S 591

Human   167 DIMLVKMASPV-SITW-AVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQ 229
            |:.|:::...| :.|| ....|....:.:.....|.|.|||...:........|..|.:.||..|
  Fly   592 DVALLRLPKAVNATTWIGYSCLPQPFQALPKNVDCTIIGWGKRRNRDATGTSVLHKATVPIIPMQ 656

Human   230 KCENA-YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQ--------GIISWGQDPCAITR 285
            .|... |...||..|.||..|:|..|:|.|||||||:|..:.:        ||.|:| |.||...
  Fly   657 NCRKVYYDYTITKNMFCAGHQKGHIDTCAGDSGGPLLCRDTTKPNHPWTIFGITSFG-DGCAQRN 720

Human   286 KPGVYTKVCKYVDWI 300
            |.|:|.||..||||:
  Fly   721 KFGIYAKVPNYVDWV 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	84/258 (33%)
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	84/258 (33%)