Protein Alignment KLK11 and CG18180

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_648341.1
• Gene: CG18180 / 39125
• FlyBaseID: FBgn0036024
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 80/319 - (25%)
• Similarity: 117/319 - (36%)
• Gaps: 113/319 - (35%)

Human    36 LQLILLALATGLV-----------------GGETRIIKGFECKPHSQPWQAALFEKT-----RLL 78
            ::|.||.|:..|.                 |.|.||:.|:.......|:...||.:|     ..:
  Fly     1 MKLFLLTLSAALALVAASPTGLNRTTLLSQGAEGRIVNGYPAPEGKAPYIVGLFIRTDGSNSGAV 65

Human    79 CGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYI-VHLGQH---NLQKEEG 139
            ...|:||..|:|||||||                         ...|: :|.|.:   |     |
  Fly    66 GAGTIIANDWILTAAHCL-------------------------TGDYVEIHYGSNWGWN-----G 100

Human   140 CEQTRTATESF-------------------PHPGFNN-----SLPNKDHRNDIMLVKMASPVSIT 180
            ..:.....::|                   ||..||.     .||:.:.:||        ....|
  Fly   101 AYRQTVRRDNFISHPDWPSQGGRDIGLIRTPHVDFNGLINKIPLPSMNEQND--------RYQDT 157

Human   181 WAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVC 245
            |                 |:..|||...:.  .|...|:|.::.||.:.:||.|| |::..|.:|
  Fly   158 W-----------------CVACGWGGMDNG--NLADWLQCVDVQIISNSECEQAY-GSVASTDMC 202

Human   246 ASVQEGGKDSCQGDSGGPLVC--NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 302
            .. ...||..|.||||||||.  |..|.|:|::....|  ...|..||:|..|::||::
  Fly   203 TR-HADGKSVCGGDSGGPLVTHDNARLVGVITFASVSC--HDGPSGYTRVSDYLEWIRD 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	71/281 (25%)
CG18180	NP_648341.1	Tryp_SPc	36..259	CDD:238113	72/284 (25%)