Protein Alignment KLK11 and CG10469

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 87/298 - (29%)
• Similarity: 138/298 - (46%)
• Gaps: 70/298 - (23%)

Human    35 ILQLILL---ALATGLVGGETRIIKGFECKPHSQPWQAAL---FEKTR---LLCGATLIAPRWLL 90
            ||||:|:   :|..|...|..||:.|...|....|:|..|   ||.::   .:||.|:::.||::
  Fly     2 ILQLVLIVQFSLVFGQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWII 66

Human    91 TAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGF 155
            ||||||:           .|.        |:|.:.::|:|:.....::.....|:.|  ..|..|
  Fly    67 TAAHCLQ-----------DPK--------SNLWKVLIHVGKVKSFDDKEIVVNRSYT--IVHKKF 110

Human   156 NNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL-SSRCVTAGTSCLISGWGSTSSPQLRLP-HTL 218
            :    .|...|||.|:|:...::....::|..| |::....|...:|||||.|:.   :|| ..|
  Fly   111 D----RKTVTNDIALIKLPKKLTFNKYIQPAKLPSAKKTYTGRKAIISGWGLTTK---QLPSQVL 168

Human   219 RCANITIIEHQKCENAYPGNITDTMVCASVQEGGK------------DS-----CQGDSGGPLVC 266
            :.....||.:::||..:           :.|.|||            ||     |:||||||:|.
  Fly   169 QYIRAPIISNKECERQW-----------NKQLGGKSKKVVHNGFICIDSKKGLPCRGDSGGPMVL 222

Human   267 ---NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQ 301
               :::|.||:|.|.|.....:.|.|.|:|..|:.||:
  Fly   223 DDGSRTLVGIVSHGFDGECKLKLPDVSTRVSSYLKWIK 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/274 (28%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	77/274 (28%)