Protein Alignment KLK11 and CG10477

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_648010.1
• Gene: CG10477 / 38679
• FlyBaseID: FBgn0035661
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 80/295 - (27%)
• Similarity: 132/295 - (44%)
• Gaps: 56/295 - (18%)

Human    33 MRILQLILLALAT---GLVGGET---------------RIIKGFECKPHSQPWQAALFEKTRL-- 77
            |::..:::||:||   .::..:|               ||..|.:...:..|:|..|..|:..
  Fly     1 MKVFAVLVLAIATVSADILRQDTPVHPRDSSAVPSIDGRITNGNKAAANQFPYQVGLSFKSSAGS 65

Human    78 -LCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCE 141
             .||.::||..|:||||||.|...|:|                       ::.|. .::.....:
  Fly    66 WWCGGSIIANTWVLTAAHCTKGASSVT-----------------------IYYGS-TVRTSAKLK 106

Human   142 QTRTATESFPHPGFNNSLPNKDHRNDIMLVKMAS---PVSITWAVRPLTLSSRCVTAGTSCLISG 203
            :..::::...|.|:|.:    ..||||.|:|..|   .|||.....|...||....||.:.:.||
  Fly   107 KKVSSSKFVQHAGYNAA----TLRNDISLIKTPSVTFTVSINKIALPAIASSYSTYAGQTAVASG 167

Human   204 WGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN-ITDTMVCA-SVQEGGKDSCQGDSGGPLVC 266
            ||.||...:.:...|:.|...:|.:..|:..:..: :|..::|. |:.:  |.:|||||||||..
  Fly   168 WGRTSDSSIAVATNLQYAQFQVITNAVCQKTFGSSVVTSGVICVESINK--KSTCQGDSGGPLAL 230

Human   267 NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQ 301
            |..|.|:.|:..........|..:|:|..|:|||:
  Fly   231 NNRLIGVTSFVSSKGCEKNAPAGFTRVTSYLDWIK 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	72/254 (28%)
CG10477	NP_648010.1	Tryp_SPc	39..264	CDD:214473	72/254 (28%)