Protein Alignment KLK11 and CG1299

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_647862.1
• Gene: CG1299 / 38496
• FlyBaseID: FBgn0035501
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 91/344 - (26%)
• Similarity: 141/344 - (40%)
• Gaps: 102/344 - (29%)

Human    13 SGRGLTAAKEPGARSSPLQAMRILQLILLALATG---LVGGETRIIKGFECKPHSQPWQAAL--- 71
            :|:|:|......::..|.....|.:. ||.:..|   .||...:|:.|...:..:.||.|.|
  Fly   218 TGQGITNTTPAPSQIVPKNTDEIPRR-LLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYD 281

Human    72 ------FEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLG 130
                  |:     ||.|||..|.:||||||::            .||.            .|.||
  Fly   282 DPSGSPFK-----CGGTLITARHVLTAAHCIR------------QDLQ------------FVRLG 317

Human   131 QHNLQKEEGCEQTRTATES----------FPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRP 185
            :|:|.         |.||:          ..||.:|    .::.|:|:.::.:...|..|..:.|
  Fly   318 EHDLS---------TDTETGHVDINIARYVSHPDYN----RRNGRSDMAILYLERNVEFTSKIAP 369

Human   186 LTLSSRCVTA--------GTSCLISGWGST----SSPQLRLPHTLRCANITIIEHQKCENAY--- 235
            :.|..   ||        |....::|||.|    .|.|:     |....|.|.:::.|..:|
  Fly   370 ICLPH---TANLRQKSYVGYMPFVAGWGKTMEGGESAQV-----LNELQIPIYDNKVCVQSYAKE 426

Human   236 -----PGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQ--------GIISWGQDPCAITRKP 287
                 .......::||.|..||||:|||||||||:..:..|        |::|:|.. ||....|
  Fly   427 KRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIG-CARPNVP 490

Human   288 GVYTKVCKYVDWIQETMKN 306
            |||:....::|||.:.:::
  Fly   491 GVYSSTQYFMDWIIQQVQD 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	79/293 (27%)
CG1299	NP_647862.1	CLIP	37..92	CDD:463440
		CLIP	164..216	CDD:463440
		Tryp_SPc	261..503	CDD:238113	79/292 (27%)