Protein Alignment KLK11 and etaTry

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_523692.1
• Gene: etaTry / 36217
• FlyBaseID: FBgn0011554
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 85/285 - (29%)
• Similarity: 128/285 - (44%)
• Gaps: 53/285 - (18%)

Human    33 MRILQ-LILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKT------RLLCGATLIAPRWLL 90
            :|||. |.||.:.......:.||:.|.:...:...:...|..::      ...||..::....:.
  Fly     6 LRILAVLFLLGIYAVSAQSDGRIVGGADTSSYYTKYVVQLRRRSSSSSSYAQTCGGCILDAVTIA 70

Human    91 TAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGF 155
            |||||:.             :..:.|        ::|..|..:.....|.  ....::..||..:
  Fly    71 TAAHCVY-------------NREAEN--------FLVVAGDDSRGGMNGV--VVRVSKLIPHELY 112

Human   156 NNSLPNKDHRNDIMLVKMASPVSIT--WAVRPLTLSSRCVTAGTSCLISGWGST-----SSPQLR 213
            |:|..:    |||.||.:..|:.:.  ..:..:.::|.....|....|||||.|     ||.||:
  Fly   113 NSSTMD----NDIALVVVDPPLPLDSFSTMEAIEIASEQPAVGVQATISGWGYTKENGLSSDQLQ 173

Human   214 LPHTLRCANITIIEHQKCENAY---PGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIIS 275
            .      ..:.|::.:||:.||   |  |::.|:||.:.|||||:||||||||||....|.||:|
  Fly   174 Q------VKVPIVDSEKCQEAYYWRP--ISEGMLCAGLSEGGKDACQGDSGGPLVVANKLAGIVS 230

Human   276 WGQDPCAITRKPGVYTKVCKYVDWI 300
            ||:. ||....||||..|..|.|||
  Fly   231 WGEG-CARPNYPGVYANVAYYKDWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/262 (29%)
etaTry	NP_523692.1	Tryp_SPc	27..254	CDD:214473	77/262 (29%)