Protein Alignment KLK11 and kappaTry

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 81/290 - (27%)
• Similarity: 127/290 - (43%)
• Gaps: 62/290 - (21%)

Human    40 LLALATGL-----VGG--ETRIIKGFECKPHSQPWQAAL-----FEKTRL-LCGATLIAPRWLLT 91
            ||.||.|.     :.|  |.|||.|........|:..:|     .|.:.: .|...:|:.:.|:|
  Fly     5 LLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALIT 69

Human    92 AAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFN 156
            :|.||                    |.|...::.:...|.:          ||..|:.|.:|..|
  Fly    70 SAQCL--------------------YGLPEETKLVAVAGAN----------TRNGTDGFIYPVAN 104

Human   157 -NSLPNKDH---RNDIMLVKMASPVSIT-WAVRPLTLSSRCVTAGTSCLISGWG-----STSSPQ 211
             ...||.|.   .|||.::.:.:.:.:| ..:..:.:.......|....::|||     ..||
  Fly   105 WTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSS-- 167

Human   212 LRLPHTLRCANITIIEHQKCENAY-PGNITDTMVCAS-VQEGGKDSCQGDSGGPLVCNQSLQGII 274
                :.|....:.::..::|...| .|.:|:.|:||. |.:||.|:||||:|||||.:..|.|::
  Fly   168 ----YKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLV 228

Human   275 SWGQDPCAITRKPGVYTKVCKYVDWIQETM 304
            |||:. ||....|.||..|..:||||:||:
  Fly   229 SWGRG-CARPNYPTVYCYVASFVDWIEETI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	70/264 (27%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	71/266 (27%)