Protein Alignment KLK11 and flz

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_001137622.1
• Gene: flz / 35902
• FlyBaseID: FBgn0286782
• Length: 1693
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 80/285 - (28%)
• Similarity: 118/285 - (41%)
• Gaps: 76/285 - (26%)

Human    59 EC--KPH---------------SQPWQAALFEKTRL------LCGATLIAPRWLLTAAHC----L 96
            ||  :||               :.|||..:.|.|.|      .||..||..|:::|||||    |
  Fly  1437 ECGVRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHCQPGFL 1501

Human    97 KPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPN 161
            ...|::.....:|.||.|......::.|.|||            .|...||
  Fly  1502 ASLVAVMGEFDISGDLESKRSVTKNVKRVIVH------------RQYDPAT-------------- 1540

Human   162 KDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT-AGTSCLISGWGSTSSPQLR----LPHTLRCA 221
              ..||:.|:::.|||.....:.|:.:.:.... .|....::|||     :|:    :|..|:..
  Fly  1541 --FENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWG-----RLKYGGGVPSVLQEV 1598

Human   222 NITIIEHQKCENAY--PGN---ITDTMVCASVQEGGKDSCQGDSGGPLVCNQ-----SLQGIISW 276
            .:.|||:..|:..:  .|:   |..:.:||....|.||||:||||||||..:     .|.|.:|.
  Fly  1599 QVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSH 1663

Human   277 GQDPCAITRKPGVYTKVCKYVDWIQ 301
            | ..||....||||.:...|..|::
  Fly  1664 G-IKCAAPYLPGVYMRTTFYKPWLR 1687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	79/282 (28%)
flz	NP_001137622.1	PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	76/273 (28%)