Protein Alignment KLK11 and Phae1

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_609550.1
• Gene: Phae1 / 34637
• FlyBaseID: FBgn0263234
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 85/279 - (30%)
• Similarity: 125/279 - (44%)
• Gaps: 37/279 - (13%)

Human    32 AMRILQLILLALATGLVGG--ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
            |..:|.|:.:...:|:..|  |.|::.|.....:|.|:..::.......|.|:::...||:||||
  Fly    12 ASGLLLLLGICRISGVAIGAPEGRVVGGSPAAVNSAPYAVSMQYGGTHYCAASILNANWLVTAAH 76

Human    95 CLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL 159
            ||.....:...|.|:..::                       .:|...| |.|.|..:...|:..
  Fly    77 CLTNSNQVLGSTLVAGSIA-----------------------VDGTAST-TQTRSITYFVINDLY 117

Human   160 PNKDHRNDIMLVKMASPVSITW--AVRPLTL-SSRCVTAGTSCLISGWGSTSSPQ-LRLPHTLRC 220
            .......||.::  .:|.:..|  ||.|:|| ||..|..||:.|. ||||||:.. ...|.||:.
  Fly   118 TGGTVPYDIGMI--YTPTAFVWSAAVAPVTLPSSGVVPTGTANLY-GWGSTSTTNTASYPSTLQV 179

Human   221 A-NITIIEHQKCENAY---PGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPC 281
            | |:.||....||:|.   ..::..|.:|.....||...|..|||||||....|.||:|||:.||
  Fly   180 ATNVPIISLSSCESALGTKGSDVHSTNLCTGPLTGGVSICTSDSGGPLVQGNVLIGIVSWGKLPC 244

Human   282 AITRKPGVYTKVCKYVDWI 300
            .....|.||.:|..::.||
  Fly   245 GQANSPSVYVQVSSFISWI 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/254 (30%)
Phae1	NP_609550.1	Tryp_SPc	36..266	CDD:238113	78/255 (31%)