Protein Alignment KLK11 and CG11911

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_608518.1
• Gene: CG11911 / 33206
• FlyBaseID: FBgn0031249
• Length: 277
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 127/298 - (42%)
• Gaps: 57/298 - (19%)

Human    17 LTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAAL---FEKTRLL 78
            |.||.: ||:.|..     |..::.:.|||.|      |.|.|.:|||.|:..:|   :.|...:
  Fly    12 LVAAAQ-GAKLSDK-----LAKLVPSFATGFV------INGTEAEPHSAPYIVSLATNYLKHSHI 64

Human    79 CGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQT 143
            ||.|||...|::|||||:...|.::                       :..|.|...:.:...|.
  Fly    65 CGGTLINKDWIVTAAHCISEPVGMS-----------------------IIAGLHTRAEVDELTQQ 106

Human   144 RTATESFPHPGFNNSLPNKD----HRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGW 204
            |.......|..:...:...|    |.|:..:..       .| |:|.||.||.........:.||
  Fly   107 RQVDFGRVHEKYTGGVGPYDIALLHVNESFIFN-------EW-VQPATLPSREQVHEGETHLYGW 163

Human   205 GSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN--ITDTMVCASVQEGGKDSCQGDSGGPLVCN 267
            |...|.......||:.....|:.:::|:...|.:  |.::.:|:|..:..|.:|.||||||||..
  Fly   164 GQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSACNGDSGGPLVVE 228

Human   268 -----QSLQGIISWGQDPCAITRKPGVYTKVCKYVDWI 300
                 ..|.||:|||..||.:...|.:||||..|:|||
  Fly   229 FTNAPSELIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	73/260 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	74/265 (28%)