Protein Alignment KLK11 and CG33127

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_787956.1
• Gene: CG33127 / 318893
• FlyBaseID: FBgn0053127
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 313
• Identity: 81/313 - (25%)
• Similarity: 122/313 - (38%)
• Gaps: 74/313 - (23%)

Human    28 SPLQAMRILQLILLALA---------------TGLVGGETR--IIKGFECK-PHSQPWQAALFEK 74
            |||     ..|.|||||               |..|..|.:  ||.|::.: ..:.|:..:| ..
  Fly     3 SPL-----FLLPLLALAGAAKLPHIQHLTLRDTEQVHAEIQPLIIDGYDVQGVDNVPYLVSL-SL 61

Human    75 TRL----LCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQ 135
            ||.    ||||::|..|||||||||:....:.......:|                |:.|..| :
  Fly    62 TRATYTHLCGASIIGKRWLLTAAHCVDELRTFNGDAVGTP----------------VYAGIIN-R 109

Human   136 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTL-------SSRCV 193
            ......|.|....:..|..||.:..:    ::|.|:.::........|:.:.|       |::..
  Fly   110 SNVTAAQVRYVDFASTHRSFNGNAGS----DNIALLHVSESFEYNARVQQIALPDINDDYSNKTA 170

Human   194 TAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGN--ITDTMVCASVQEGGKDSC 256
            .|      .|||.|..........|:.|...::....|:...|.:  :|...||:.|:     :|
  Fly   171 AA------YGWGLTDPDGDEYSKELQYAFAPLLNSTGCKELLPADAPLTAQQVCSQVK-----TC 224

Human   257 QGDSGGPLVC-----NQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETM 304
            .||.|.||:.     ...|.|:.||...||....:|.|||.|..|:.||.:|:
  Fly   225 YGDGGTPLIYWPITGPAELVGLGSWSYMPCGYANRPTVYTSVPPYIGWIHQTI 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	66/267 (25%)
CG33127	NP_787956.1	Tryp_SPc	41..273	CDD:214473	66/264 (25%)