Protein Alignment KLK11 and CG33458

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 76/311 - (24%)
• Similarity: 123/311 - (39%)
• Gaps: 81/311 - (26%)

Human    38 LILLALATGLVGGET--------------RIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRW 88
            |.||.|..|:..|.:              ||..|.:......||.|.|...::.:||.:|:...:
  Fly     8 LALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWF 72

Human    89 LLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTAT------ 147
            :||||||.:                ..|      ::.:|.||:::..::..|.::..|.
  Fly    73 VLTAAHCFR----------------DKN------AKVLVRLGENDASQKIDCNESECAAPHLEYM 115

Human   148 --ESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSR-----CVTAGTSCLISGWG 205
              :...||.:..:     |..||.|.|:...|..|.::||:.|...     .|......:|:|||
  Fly   116 IMQKLIHPLYRTA-----HYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWG 175

Human   206 STSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCA--SVQEGGKDSCQGDSGGPL---- 264
            :|::.:  :...|:...|..|:...|...:...:..|.:||  |....||    |||||||
  Fly   176 ATNASE--VSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVGK----GDSGGPLGSMV 234

Human   265 ---VCNQSLQ-GIISWGQDPCAITRKP----GVYTKVCKYVDWIQETMKNN 307
               ...:..| ||:|.       .|:|    .|:|.:..|.:||..|:..|
  Fly   235 DYKYAKRFFQFGIVSH-------LRQPFHGVSVFTNILSYSNWIHRTIITN 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	66/273 (24%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	67/275 (24%)