Protein Alignment SLC27A2 and Acsl

DIOPT Version :10

• Sequence 1: NP_003636.2
• Gene: SLC27A2 / 11001
• HGNCID: 10996
• Length: 620
• Species: Homo sapiens
• Sequence 2: NP_001260810.1
• Gene: Acsl / 46068
• FlyBaseID: FBgn0263120
• Length: 728
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 119/647 - (18%)
• Similarity: 221/647 - (34%)
• Gaps: 192/647 - (29%)

Human    80 TYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLL 144
            |:.:.:|.:....|.|.: ||.:..:.:.:.......::....|..|....:..:...:....:.
  Fly   148 TFTEAERTAANFGRGLRE-LGQKPRENIVIFAETRAEWMIAAHGCFKQAMPIVTVYATLGDDGVA 211

Human   145 HCFQCCGAKVLLVSPELQAAVEEIL---PSLK-----------------KDDVSIYYVSRTSNTD 189
            ||........::.|.:|....:.:|   |.:|                 |:.|.|...::...|
  Fly   212 HCITETEVTTVITSHDLLPKFKTLLDKCPLVKTIIYIEDQLQKTETTGFKEGVKILPFNQVVKT- 275

Human   190 GIDSFLDKV----DEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQR-IWYGTGLT 249
            |.||..:.|    |::                  |:.:||||:||.||..:::|:. |....|..
  Fly   276 GQDSKFEHVPPKGDDI------------------AIIMYTSGSTGTPKGVLLSHKNCIATMKGFV 322

Human   250 FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKF----SASQFWDDCRKYNVTVIQ 310
            .:..:..|||:...||..| ...|:....|::.|..:...|..    ::|:....| |.:.||::
  Fly   323 DMVPIYPDDVLIGFLPLAH-VFELVAESVCLMTGVPIGYSTPLTLIDTSSKIKRGC-KGDATVLK 385

Human   311 ---------------------------YIGELLRYLCNSPQKPNDRDH----------------- 331
                                       :...|.::|.....|...|.:
  Fly   386 PTCMTSVPLILDRISKGINDKVNSGSAFKKSLFKFLYQYKVKWVQRGYKTPLIDKLVFKKVAKLM 450

Human   332 --KVRLALGNG--LRGDVWRQFVKRFGDICIYEFYAATEGNIGF-------MNYARKVGAVGRVN 385
              |||:.:..|  |..|...| :|....:.:.:.|..||...|.       |.|.|..|.:
  Fly   451 GGKVRIIMSGGAPLSADTHEQ-IKTCLCLELIQGYGLTETTSGATVMDYRDMTYGRTGGPL---- 510

Human   386 YLQKKIITYDLIKYDVEKDEPVRDENGYCVR---VPKGEVGLLV---CKITQLTPFNGYAGAKAQ 444
                .:....|:.:         :|..|.|.   .|:|||  |:   | ::|     ||.....:
  Fly   511 ----TVCDIRLVNW---------EEGNYRVTNKPYPQGEV--LIGGEC-VSQ-----GYYKLPGK 554

Human   445 TEKKKLRDVFKK-GDLYFNSGDLLMVDHENFIYFHDRVGDTFRWK-GENVATTEVADTVGLVDFV 507
            |.:    |.|:: |..:|.:||:..:..:..:...||..|..:.: ||.|:..:|...:.....:
  Fly   555 TNE----DFFEEDGQRWFKTGDIGEIQADGVLKIIDRKKDLVKLQAGEYVSLGKVESELKTCGII 615

Human   508 QEVNVYGVHVPDHEGRIGMASIKMKENH-------------EFD--------GKKLFQHIADY-- 549
            :.:.|||    |...:..:|.:...:||             .|:        .|.:.:.||::
  Fly   616 ENICVYG----DPTKQYTVALVVPNQNHLEELAQKHGLGDKSFEELCSSPIIEKAILKEIAEHAR 676

Human   550 ---LPSYARPRFLRI------QDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMY 602
               |..|..|..:.:      .|...:|..||.::..:.:.            :..|..:||
  Fly   677 KCKLQKYEVPAAITLCKEVWSPDMGLVTAAFKLKRKDIQDR------------YQHDINRMY 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A2	NP_003636.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	119/647 (18%)
Acsl	NP_001260810.1	LC_FACS_euk1	142..714	CDD:341294	116/621 (19%)