DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC27A3 and CG11659

DIOPT Version :9

Sequence 1:	NP_077306.3	Gene:	SLC27A3 / 11000	HGNCID:	10997	Length:	683	Species:	Homo sapiens
Sequence 2:	NP_650829.1	Gene:	CG11659 / 42352	FlyBaseID:	FBgn0038731	Length:	546	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	90/420 - (21%)
Similarity:	154/420 - (36%)	Gaps:	109/420 - (25%)

- Green bases have known domain annotations that are detailed below.

Human   250 HPAG---ISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGF 311
            ||..   |.:::|....|...|......:.|::...|    :|||||.|||..|::.:.: ..|.
  Fly   159 HPLDSIKIDEVVATPIEENFQPAKLEKGNDQTLAILC----SSGTTGTPKAVTITNSRHI-LAGN 218

Human   312 YQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGAT--VVLKSKFSAGQFWEDCQQHRVTVFQY 374
            |.|.   ..||.|....|..::|.|..|..  |:.:|  ::..:.|.........::::||
  Fly   219 YHLT---TADVQYSHNTLDWITGLLTTITS--GVFSTTRIIADNAFDPAFALRIIEEYKVT---- 274

Human   375 IGELCRYLVNQPPSKAE---------------------RGHKVRLAVGSGLRPDTWERFVRRFGP 418
                   ...||||...                     .|.:..|.|..|:|        .|...
  Fly   275 -------WTIQPPSSMALMINCPDFETCDLSSLRCYMFGGSRAALEVQKGIR--------SRLSH 324

Human   419 LQVLETYGLTE-GNVATIN--YTGQRGAVGRASWLYKHIFPFSLIRYDVTTG--EPIRDPQGHCM 478
            ..:...||.|| |.:||||  :..:.|:||:                 :..|  ..|::..|..:
  Fly   325 NCLQFVYGFTELGAMATINCHFDEKTGSVGQ-----------------LVNGLKMKIKNDDGESL 372

Human   479 ATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDR 543
              .|.|.|.:.  :.....:.||.|..  .:.:.::|...    ::::|||...|..|||...||
  Fly   373 --GPDEIGEVC--IMNNQHWSGYYGNE--VETRNMRDSLG----WYHSGDLGYMDRDGFLYIMDR 427

Human   544 TGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGV--TVPGHEGRAGMAALVLRPPHALDLMQLY 606
            ..:..:::.......::..|...:..:.||.|:|:  .:.|.|   ..||:|.:....|:
  Fly   428 KKEMLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDE---AAAAVVKKLGSELE----- 484

Human   607 THVSENLPPYARPRFLRLQESLATTETFKQ 636
               ::::..|.|.|         |...:||
  Fly   485 ---AQDVVDYVRSR---------TDSKYKQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A3	NP_077306.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..145
SLC27A3	NP_077306.3	hsFATP2a_ACSVL_like	163..673	CDD:213304	90/420 (21%)
CG11659	NP_650829.1	CaiC	26..523	CDD:223395	90/420 (21%)
CG11659	NP_650829.1	AFD_class_I	47..522	CDD:302604	90/420 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840