DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC27A3 and CG9993

DIOPT Version :9

Sequence 1:	NP_077306.3	Gene:	SLC27A3 / 11000	HGNCID:	10997	Length:	683	Species:	Homo sapiens
Sequence 2:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	91/354 - (25%)
Similarity:	144/354 - (40%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

Human   248 GTHPA--GISDLLAEVSAEVDGPVPGY-----LSSPQSITDTCLYIFT-SGTTGLPKAARISHLK 304
            ||.|.  .|.||||      || ..||     .:.|....|...:|.| ||.|||||....||..
  Fly   157 GTLPGVRNIQDLLA------DG-CTGYDEKTLFACPHLCGDDTAFIITSSGVTGLPKGVTRSHRS 214

Human   305 ILQCQGFYQLCGVHQEDVIYLALPLYHMS------GSLLGIVGCMGIGATVVLKSKFSAGQFWED 363
            :|......||  ...:.|::...|||.:|      .||:.  ||    ..::....||...|.:.
  Fly   215 LLNSAKIPQL--FTSDTVLFCFSPLYWISCIFTLLASLVN--GC----RRIITNRPFSVAYFADL 271

Human   364 CQQHRV----TVFQYIGELCRYLVNQPPSKAERGHKVR-----LAVGSGLRPDTWERFVRRFGPL 419
            .::|:|    ||..::.     |:.:.|.:.|...|::     :..||.:....|.:.....|..
  Fly   272 VERHQVSFVLTVPHHMA-----LLAKSPERQELAAKMQCVQSFVCSGSKVPMGIWRQLYELLGAN 331

Human   420 QVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGE 484
            :....|||||....:.|..|..|:.||   |.:::    .:|        :.||.|..:  .|.:
  Fly   332 RFAVLYGLTETGGISKNVGGPLGSEGR---LLRNV----QVR--------VVDPHGQSL--GPNQ 379

Human   485 PGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFR 549
            .|.::..::.:  :.||...|:..|..:     .|...:..|||....||:|.|.|..|..|.|:
  Fly   380 TGQILVRLNLR--WGGYYHNPQETQVTV-----TPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFK 437

Human   550 WKGENVATTEVAEVFEALDFLQEVNVYGV 578
            :....:...::.:|...|..:.||.|:|:
  Fly   438 YNHFPIYPKQIEDVILHLPGVHEVAVFGI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A3	NP_077306.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	119..145
SLC27A3	NP_077306.3	hsFATP2a_ACSVL_like	163..673	CDD:213304	91/354 (26%)
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	91/354 (26%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	91/354 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149046
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840