Protein Alignment SLC27A4 and Fatp2

DIOPT Version :10

• Sequence 1: XP_047278620.1
• Gene: SLC27A4 / 10999
• HGNCID: 10998
• Length: 654
• Species: Homo sapiens
• Sequence 2: NP_995925.2
• Gene: Fatp2 / 37657
• FlyBaseID: FBgn0265187
• Length: 714
• Species: Drosophila melanogaster
• Alignment Length: 663
• Identity: 298/663 - (44%)
• Similarity: 403/663 - (60%)
• Gaps: 37/663 - (5%)

Human     9 IATMLLGASLVGVLLFSKLVLKLPWTQVG---FSLLFLYLGSGGWRFIRVFIKTIRRDIFGGLVL 70
            :|.:|...|  |::|:    .:.||..|.   .:|:.:.|...|||:..:...|..||.......
  Fly    66 LAPVLTAIS--GLILY----YQGPWYGVATLYAALISILLVRPGWRWFYIAAVTTPRDTVALFAY 124

Human    71 LKVKAKVRQCLQERRTVPI--LFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARG 133
            ::|...:::  |||:.:.|  :|.|.|.|.|||.|::.|  ...|||||::|:|:.|||...:.|
  Fly   125 IRVLLFIKR--QERKNLNIGDIFESNVARQPDKLAIVSE--SQQWTFRQVNEHSNRVANVFHSHG 185

Human   134 LASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAI 198
            ...|||..:.:|||.|||..|||::|:||...|||||||..:|.|.:|..:..||::|:...||:
  Fly   186 YKKGDVVGLLLENRAEFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTALIYGASFRSAV 250

Human   199 CEVHASLDPSLSLFCSGSWEPGAVPPS-------TEHLDPLLKDAPKHLPSCPDK--------GF 248
            .::...|...:.|:.........|..|       .:.|:.||:.|.|      ||        ..
  Fly   251 MDIAKDLPAHVGLYQFNDESNQEVVASEGLSQGLAQQLNGLLETAAK------DKVAAGASRADH 309

Human   249 TDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCL 313
            .|||.||||||||||||||::.||||:.:||.::|....:..|:.|..|||||:||.::.:||.|
  Fly   310 HDKLVYIYTSGTTGLPKAAVITHSRYFFIAAGIHYTLGFKDQDVFYTPLPLYHTAGGVMSMGQAL 374

Human   314 LHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSI 378
            |.|.|||||||||||.::.||.::.||:.|||||:.||:|..|....:..|||||..|||||..|
  Fly   375 LFGSTVVIRKKFSASGYFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNGLRPQI 439

Human   379 WTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGP 443
            |..|..||.|.:|.|||||||.|.::.|.||.|||.||.||||..:|||.:::.:..|.|.:|..
  Fly   440 WPQFVERFGIRKVGEFYGATEGNANIMNNDSTVGAIGFISRILPQIYPISIIKADPHTGEPLRNS 504

Human   444 DGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELG 508
            .|:|..|:..|||..||:|::.:|.|.|.||::|.|::||:..|||.|||.|:::||:||.||.|
  Fly   505 QGLCERCEADEPGVFVGKIVRGNPCREFLGYVDQKASSKKVVHDVFSKGDMAFISGDLLVADERG 569

Human   509 YLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDL 573
            ||||:||||||||||||||||:|||..||.|....||.||||.:|.|||||||||:..||...::
  Fly   570 YLYFKDRTGDTFRWKGENVSTSEVEAQLSNLAGYKDVIVYGVSIPNTEGRAGMAAIYDPTREVNV 634

Human   574 ERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVP 638
            .:....|.|.||.||||.|||.|.::..|||:|.:|.||:::||:|.|:.|.|||.... |.|.|
  Fly   635 SQLGVELAKSLPNYARPQFLRFLRKIDLTGTFKLRKVELQQQGFNPEIIDDELFYAQPD-GVYAP 698

Human   639 LDQEAYSRIQAGE 651
            |....|.||...|
  Fly   699 LTPSVYERIVRNE 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC27A4	XP_047278620.1	hsFATP4_like	110..619	CDD:341262	254/523 (49%)
Fatp2	NP_995925.2	Adenylate forming domain, Class I superfamily	163..680	CDD:473059	254/522 (49%)