Protein Alignment METAP2 and und

DIOPT Version :10

• Sequence 1: NP_006829.1
• Gene: METAP2 / 10988
• HGNCID: 16672
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_477373.1
• Gene: und / 34294
• FlyBaseID: FBgn0283478
• Length: 448
• Species: Drosophila melanogaster
• Alignment Length: 459
• Identity: 297/459 - (64%)
• Similarity: 355/459 - (77%)
• Gaps: 29/459 - (6%)

Human    28 ASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDG 92
            |:|.|...:.|::||.|           |:.:.       .||...:.:...|..:::...:||.
  Fly    11 AATPEIGEEVKKQKKPK-----------PNNKK-------LRQEAAAKIASGEGGDEELTTNGDA 57

Human    93 DGAT-----GKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQ---DGRTAAWR 149
            ..||     .|||..|.||.|   |||||::||..|||:|.||:|:..|:|..:   |.|||..|
  Fly    58 KPATPAAQPAKKKGNKGKKSG---QTDPPTIPIAKLYPDGNFPEGEIVEHPTPKDMPDDRTAKDR 119

Human   150 TTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLN 214
            .|||||:|||:.:.:|:.:.|:|||||||.|:|:..:||||||||:|||:||:.:|:||.||||.
  Fly   120 FTSEEKRALDRINTDIYQELRQAAEAHRQTRQYMQRYIKPGMTMIQICEELENTARRLIGENGLE 184

Human   215 AGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKA 279
            ||||||||||||:|||||||||||.|||||||:|||||||||.|||||||||:|||.|||.||:|
  Fly   185 AGLAFPTGCSLNHCAAHYTPNAGDPTVLQYDDVCKIDFGTHIKGRIIDCAFTLTFNNKYDKLLQA 249

Human   280 VKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV 344
            ||:||||||:.|||||||||:|.||||||||||:|:|||||.:|.|||||||||..|||||||||
  Fly   250 VKEATNTGIREAGIDVRLCDIGAAIQEVMESYEIELDGKTYPIKAIRNLNGHSISPYRIHAGKTV 314

Human   345 PIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN 409
            |||||||:|||||.|.||||||||||:|:|||||:|||||||||:..||:||..:|.||..||:|
  Fly   315 PIVKGGESTRMEEDEFYAIETFGSTGRGLVHDDMDCSHYMKNFDLPFVPLRLQSSKQLLGTINKN 379

Human   410 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSR 474
            |||||||:|||||.|.:||.||||:|||.|||:.|||||||||.||||:||||:|||||||||||
  Fly   380 FGTLAFCKRWLDRAGATKYQMALKDLCDKGIVEAYPPLCDIKGCYTAQYEHTIMLRPTCKEVVSR 444

Human   475 GDDY 478
            ||||
  Fly   445 GDDY 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
METAP2	NP_006829.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..122		29/98 (30%)
		PTZ00053	<107..478	CDD:240246	274/373 (73%)
und	NP_477373.1	PTZ00053	<79..448	CDD:240246	273/368 (74%)