Protein Alignment FERMT2 and fermt2

DIOPT Version :10

• Sequence 1: XP_006720071.1
• Gene: FERMT2 / 10979
• HGNCID: 15767
• Length: 706
• Species: Homo sapiens
• Sequence 2: XP_005158972.1
• Gene: fermt2 / 553051
• ZFINID: ZDB-GENE-050506-132
• Length: 695
• Species: Danio rerio
• Alignment Length: 706
• Identity: 634/706 - (89%)
• Similarity: 673/706 - (95%)
• Gaps: 11/706 - (1%)

Human     1 MALDGIRMPDGCYADGTWELSVHVTDLNRDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWW 65
            ||||||||||||||||||||.:|||||||||:||||||:||||||||||||||||||||||||||
Zfish     1 MALDGIRMPDGCYADGTWELKMHVTDLNRDVSLRVTGEIHIGGVMLKLVEKLDVKKDWSDHALWW 65

Human    66 EKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTF 130
            |||:|||||||||||||||||||:|.||||||||||||||||:::||||||||||||||||||||
Zfish    66 EKKKTWLLKTHWTLDKYGIQADARLLFTPQHKLLRLQLPNMKHMRVKVNFSDRVFKAVSDICKTF 130

Human   131 NIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITPGSGTDVLYIGPLKGSIYSSPGL 195
            |||||||||||:||||| |||||||:| :|:|.|||||||:||||.:|||||||:||||||||||
Zfish   131 NIRHPEELSLLRKPRDP-KKKKKKLED-AEEETLELEGPLLTPGSASDVLYIGPVKGSIYSSPGL 193

Human   196 YSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKIN 260
            ||||||||||:.|||||||||||||||.||||||.|||||||||||:||.||:|||:||||||||
Zfish   194 YSKTMTPTYDSRDGSPLSPTSAWFGDSPLSEGNPSILAVSQPITSPDILVKMYKPQSLLDKAKIN 258

Human   261 QGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIECTEEEM 325
            |||||||||||||||||||.|||||||:|||||||||||||:|||||||||||||||||||||||
Zfish   259 QGWLDSSRSLMEQDVKENEVLLLRFKYHSFFDLNPKYDAIRVNQLYEQAKWAILLEEIECTEEEM 323

Human   326 MMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYI 390
            ||||||||||||||||:|:||:|||:|||||||||||||||||||||||..|||||||||||||:
Zfish   324 MMFAALQYHINKLSIMSSDNHMNNSEKEVDEVDAALSDLEITLEGGKTSNTLGDITSIPELADYV 388

Human   391 KVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLL 455
            ||||||||||||||||||||||.:||||||:||:.||||||||||||||||||||||||||||||
Zfish   389 KVFKPKKLTLKGYKQYWCTFKDITISCYKSREEAHGTPAHQMNLRGCEVTPDVNISGQKFNIKLL 453

Human   456 IPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIP 520
            ||||:||||||||||.|||||.||||||||||||||||||||||||||||||||||:|||||:|
Zfish   454 IPVADGMNEIWLRCDTEKQYAQWMAACRLASKGKTMADSSYNLEVQNILSFLKMQHMNPDPQII- 517

Human   521 EQITTDITPECLVSPRYLKKYKNKQEKGCKKHMPGYIRDLITARILEAHQNVAQMSLIEAKMRFI 585
            |.|||||.|||||||||||||||||        ||::||||:|||||||||||||||||||||||
Zfish   518 EPITTDINPECLVSPRYLKKYKNKQ--------PGFVRDLISARILEAHQNVAQMSLIEAKMRFI 574

Human   586 QAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMV 650
            ||||||||||||||:|:||||||:|||||.|||||||||.|||||||||||||||||||||||||
Zfish   575 QAWQSLPEFGITHFLAKFQGGKKDELIGITYNRLIRMDAGTGDAIKTWRFSNMKQWNVNWEIKMV 639

Human   651 TVEFADEVRLSFICTEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV 706
            |||||||..|:|||.|||||||||||||||||||||||||||||||||||||||||
Zfish   640 TVEFADEPSLAFICAEVDCKVVHEFIGGYIFLSTRAKDQNESLDEEMFYKLTSGWV 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FERMT2	XP_006720071.1	FERM_F0_KIND2	17..96	CDD:340701	71/78 (91%)
		FERM_F1_KIND2	97..288	CDD:340704	167/190 (88%)
		B41	<252..>335	CDD:214604	78/82 (95%)
		PH_fermitin	384..508	CDD:269943	114/123 (93%)
		FERM_M	<466..599	CDD:459788	114/132 (86%)
		FERM_C_fermitin	593..684	CDD:270026	81/90 (90%)
fermt2	XP_005158972.1	FERM_F0_KIND2	17..96	CDD:340701	71/78 (91%)
		FERM_F1_KIND2	97..286	CDD:340704	167/190 (88%)
		B41	<253..>333	CDD:214604	76/79 (96%)
		PH_fermitin	382..506	CDD:269943	114/123 (93%)
		FERM_M	<464..588	CDD:459788	114/132 (86%)
		PH-like	582..673	CDD:473070	81/90 (90%)