| Sequence 1: | NP_006818.3 | Gene: | TMED10 / 10972 | HGNCID: | 16998 | Length: | 219 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_572754.1 | Gene: | p24-1 / 32140 | FlyBaseID: | FBgn0030341 | Length: | 210 | Species: | Drosophila melanogaster |
| Alignment Length: | 215 | Identity: | 56/215 - (26%) |
|---|---|---|---|
| Similarity: | 95/215 - (44%) | Gaps: | 33/215 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Human 14 FPLALLLLFLLGPRLVLAI--SFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGG-LRSHLK 75
Human 76 ITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVE--AKNYEEI 138
Human 139 AKVEKLKPLEVELRRLEDLSESI---VNDF----AYMKKREEEMRDTNESTNTRVLYFSIFSMFC 196
Human 197 LIGLATWQVFYLRRFFKAKK 216 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| TMED10 | NP_006818.3 | Required for interaction with STX17. /evidence=ECO:0000269|PubMed:21545355 | 1..142 | 34/132 (26%) | |
| EMP24_GP25L | 31..213 | CDD:426051 | 51/193 (26%) | ||
| Required for TMED10 and TMED2 cis-Golgi network localization | 147..178 | 9/37 (24%) | |||
| Interaction with COPG1 | 204..219 | 6/13 (46%) | |||
| Interaction with ARF1 and IL1B. /evidence=ECO:0000269|PubMed:11726511, ECO:0000269|PubMed:32272059 | 207..219 | 5/10 (50%) | |||
| COPI vesicle coat-binding | 211..219 | 3/6 (50%) |