DRSC/TRiP Functional Genomics Resources

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Protein Alignment YWHAQ and 14-3-3epsilon

DIOPT Version :9

Sequence 1:NP_006817.1 Gene:YWHAQ / 10971 HGNCID:12854 Length:245 Species:Homo sapiens
Sequence 2:NP_732309.1 Gene:14-3-3epsilon / 42186 FlyBaseID:FBgn0020238 Length:262 Species:Drosophila melanogaster


Alignment Length:243 Identity:158/243 - (65%)
Similarity:190/243 - (78%) Gaps:2/243 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     2 EKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIE 66
            |:...:.||||||||||||:|...||.|.....||:.|||||||||||||:|.||::||:|:|||
  Fly     3 ERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIE 67

Human    67 QKTDT--SDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYL 129
            ||.:.  :::||::||.||.:||.|||.||:.:|.:|:|:||..||:.||||||.||||||.|||
  Fly    68 QKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYL 132

Human   130 AEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKT 194
            ||.|.|.|||...:||..||:.|.||:..::.||||||||||||||||||||||:|:.||.|||.
  Fly   133 AEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197

Human   195 AFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEG 242
            |||:||||||||:|:||||||||||||||||||||||...||.|...|
  Fly   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAG 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
YWHAQNP_006817.1 14-3-3_theta 1..234 CDD:206759 154/233 (66%)
14-3-3epsilonNP_732309.1 14-3-3_epsilon 4..233 CDD:206757 150/228 (66%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53683
OrthoDB 1 1.010 - - D1176818at2759
OrthoFinder 1 1.000 - - FOG0000128
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.930

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