Protein Alignment YWHAQ and 14-3-3zeta

DIOPT Version :9

• Sequence 1: NP_006817.1
• Gene: YWHAQ / 10971
• HGNCID: 12854
• Length: 245
• Species: Homo sapiens
• Sequence 2: NP_001014515.1
• Gene: 14-3-3zeta / 36059
• FlyBaseID: FBgn0004907
• Length: 248
• Species: Drosophila melanogaster
• Alignment Length: 245
• Identity: 189/245 - (77%)
• Similarity: 213/245 - (86%)
• Gaps: 0/245 - (0%)

Human     1 MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSI 65
            ::|.||:||||||||:|||||||..||:|||.|.|||||||||||||||||||.|||:|||||||
  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68

Human    66 EQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLA 130
            ||||:.|.:|.||.::|||:||.|||.||..||.|||||||..|:|||||||||||||||:||||
  Fly    69 EQKTEASARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNPESKVFYLKMKGDYYRYLA 133

Human   131 EVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTA 195
            |||.||.|...:|:||.|||:||||||.:||||||||||||||||||||||||:|:.||.|||.|
  Fly   134 EVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQLAKQA 198

Human   196 FDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN 245
            ||:|||||||||||||||||||||||||||||||||:.|:|.:..||.:|
  Fly   199 FDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGDN 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YWHAQ	NP_006817.1	14-3-3_theta	1..234	CDD:206759	184/232 (79%)
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	182/228 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159672
Domainoid	1	1.000	363	1.000	Domainoid score	I947
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.960