Protein Alignment RAB40B and Rab11

DIOPT Version :10

• Sequence 1: NP_006813.1
• Gene: RAB40B / 10966
• HGNCID: 18284
• Length: 278
• Species: Homo sapiens
• Sequence 2: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 75/214 - (35%)
• Similarity: 121/214 - (56%)
• Gaps: 19/214 - (8%)

Human     4 LGSPVRAYDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLW 68
            :|:....||:|.|.:|:|||.|||..:|:...............|:::.|.:|.:||:.:|.|:|
  Fly     1 MGAREDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIW 65

Human    69 DTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHA-PGVPKILVGNRLHLAF 132
            ||:||.|:..|..:|.|||.|.:||||||...:::.::||::|:.:|| ..:..:||||:..|..
  Fly    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRH 130

Human   133 KRQVPTEQAQAYAERLGVTFFEVSPLCNFNITESF----TELARIVLLRHGMD----RLWRPSKV 189
            .|.|||::|:.:|||.|::|.|.|.|.:.|:..:|    ||:.|||..:...|    .:.|||.|
  Fly   131 LRSVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNV 195

Human   190 ----------LSLQDLCCR 198
                      ..::..||:
  Fly   196 EPIDVKPTVTADVRKQCCQ 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB40B	NP_006813.1	Rab40	9..278	CDD:133321	74/209 (35%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		0/7 (0%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		7/15 (47%)
		SOCS_Rab40	187..229	CDD:239711	4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..278
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	63/163 (39%)