Protein Alignment RAB40B and Rab10

DIOPT Version :10

• Sequence 1: NP_006813.1
• Gene: RAB40B / 10966
• HGNCID: 18284
• Length: 278
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 79/168 - (47%)
• Similarity: 105/168 - (62%)
• Gaps: 1/168 - (0%)

Human     9 RAYDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLWDTSGQ 73
            :.||.|.|.||:|||.|||..||....|.|..|.:....|||:|..|:.|.|:::|||:|||:||
  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68

Human    74 GRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHA-PGVPKILVGNRLHLAFKRQVP 137
            .||.||..||.|||.|::|||||.|..||:.|.:|::.||||| ..|.|:::||:..:..||.|.
  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133

Human   138 TEQAQAYAERLGVTFFEVSPLCNFNITESFTELARIVL 175
            .|:.:|.|...|:.|.|.|...|.||..:|.|||..:|
  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAIL 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB40B	NP_006813.1	Rab40	9..278	CDD:133321	79/168 (47%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		10/15 (67%)
		SOCS_Rab40	187..229	CDD:239711
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..278
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	78/165 (47%)