Protein Alignment RAB40B and Rab35

DIOPT Version :10

• Sequence 1: NP_006813.1
• Gene: RAB40B / 10966
• HGNCID: 18284
• Length: 278
• Species: Homo sapiens
• Sequence 2: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 199
• Identity: 79/199 - (39%)
• Similarity: 110/199 - (55%)
• Gaps: 9/199 - (4%)

Human     9 RAYDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDYKTTTILLDGRRVKLQLWDTSGQ 73
            |.:|.|.|.|::|||.|||..:|....|......|....|:|:|..|:.::|.|||||:|||:||
  Fly     3 RGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQ 67

Human    74 GRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDRWIKEIDEHAPGVPKILVGNRLHLAFKRQVPT 138
            .||.||..:|.||..|||:|||:.|..||..:.||::||..:...|.|:||||:.....::.|.|
  Fly    68 ERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDVVKKVLVGNKNDDPDRKVVIT 132

Human   139 EQAQAYAERLGVTFFEVSPLCNFNITESFTELARIVL---LR-----HGMDRL-WRPSKVLSLQD 194
            |.||.:|:::.:..||.|...|.|:...|..:.|.||   ||     ...|.| .:|:...|...
  Fly   133 EDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKGSKGG 197

Human   195 LCCR 198
            .|||
  Fly   198 KCCR 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB40B	NP_006813.1	Rab40	9..278	CDD:133321	79/199 (40%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		9/15 (60%)
		SOCS_Rab40	187..229	CDD:239711	4/12 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..278
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	77/197 (39%)