DRSC/TRiP Functional Genomics Resources

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Protein Alignment TOMM34 and CG1847

DIOPT Version :9

Sequence 1:NP_006800.2 Gene:TOMM34 / 10953 HGNCID:15746 Length:309 Species:Homo sapiens
Sequence 2:NP_001368980.1 Gene:CG1847 / 32144 FlyBaseID:FBgn0030345 Length:390 Species:Drosophila melanogaster


Alignment Length:252 Identity:53/252 - (21%)
Similarity:94/252 - (37%) Gaps:72/252 - (28%)


- Green bases have known domain annotations that are detailed below.


Human    86 KPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLV 150
            ||..||......|:...:.|.|...:||...::                    |:.::|.||.|.
  Fly   108 KPEERRHCCGMTLQNEGIGYTDLDELLQNPSDL--------------------EFIIELFSIELP 152

Human   151 PVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEK 215
            ....::||..  |::.|.:|.|                      .|:|.||...|.....:|...
  Fly   153 EQYEKERWQM--SDDEKMLATS----------------------TLRERGNNFYKASRFTEAETC 193

Human   216 YSESL------------------LCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVK 262
            |.|::                  ..:.:::....|.|.|.|:...:...::.|.|.|.||.:|||
  Fly   194 YREAVGIVEQLMLKEKPHDEEWQELAAIKTPLLLNYAQCRLIAGDFYAVIEHCNEVLTLDPRNVK 258

Human   263 AFYRRAQAH-------KALKDYKSSF---ADISNLLQIEPRNGPAQKLRQEVKQNLH 309
            |.:|||:||       :|.:|:..:.   |.:.:.:..|.::...|:..:.|:..:|
  Fly   259 ALFRRAKAHAGAWNPAQARRDFLDALALDASLKSTVSKELKSIEDQQQARNVQDRIH 315

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TOMM34NP_006800.2 TPR 1 9..42
TPR repeat 9..37 CDD:276809
PLN03088 <12..>294 CDD:330826 50/235 (21%)
TPR repeat 50..80 CDD:276809
TPR 2 51..84
TPR repeat 85..113 CDD:276809 7/26 (27%)
TPR 3 86..118 9/31 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..189 4/27 (15%)
TPR 4 193..226 8/50 (16%)
TPR repeat 193..221 CDD:276809 8/45 (18%)
TPR repeat 226..256 CDD:276809 7/29 (24%)
TPR 5 227..260 9/32 (28%)
TPR repeat 261..289 CDD:276809 11/37 (30%)
TPR 6 262..294 11/41 (27%)
CG1847NP_001368980.1 FKBP_C 23..>92 CDD:395196
3a0801s09 150..>308 CDD:273380 38/181 (21%)
TPR repeat 173..217 CDD:276809 8/43 (19%)
TPR repeat 222..252 CDD:276809 7/29 (24%)
TPR repeat 257..285 CDD:276809 10/27 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1535
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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