Protein Alignment CBX1 and HP1e

DIOPT Version :10

• Sequence 1: NP_006798.1
• Gene: CBX1 / 10951
• HGNCID: 1551
• Length: 185
• Species: Homo sapiens
• Sequence 2: NP_649878.1
• Gene: HP1e / 41108
• FlyBaseID: FBgn0037675
• Length: 174
• Species: Drosophila melanogaster
• Alignment Length: 162
• Identity: 59/162 - (36%)
• Similarity: 96/162 - (59%)
• Gaps: 19/162 - (11%)

Human    16 EEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKS 80
            ||.|||:||::||||...|:::||:||..:||||||||...:|||..|| :.::|||:.
  Fly    22 EETEEYIVERILDRRHYMGQLQYLVKWLDYSDEDNTWESAADLDCHSLI-DSIESQKSL------ 79

Human    81 EGGKRKADSDSEDKGEESKPKKKKEES----EKPRGFARGLEPERIIGATDSSGELMFLMKWKNS 141
               ||..:.:::   .|:|.|:.|.:.    :.|  |..|...:.|:....::||:.||:::.:.
  Fly    80 ---KRGQELNNQ---YETKAKRLKIDPCLVVDSP--FNHGFTAQEILKGAKNNGEISFLIRFWHL 136

Human   142 DEADLVPAKEANVKCPQVVISFYEERLTWHSY 173
            |:..:||:..|.|:.||:|:.|||....:|.|
  Fly   137 DQPQVVPSGIAYVEIPQMVLKFYENHCNFHDY 168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CBX1	NP_006798.1	CD_HP1beta_Cbx1	20..69	CDD:349297	26/48 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		15/64 (23%)
		CSD_HP1beta_Cbx1	112..169	CDD:349301	18/56 (32%)
HP1e	NP_649878.1	CD_CSD	27..71	CDD:349274	25/44 (57%)
		CSD_HP1e_insect	111..163	CDD:349337	17/51 (33%)