DRSC/TRiP Functional Genomics Resources

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Protein Alignment EHD1 and CG9297

DIOPT Version :10

Sequence 1:NP_001269374.1 Gene:EHD1 / 10938 HGNCID:3242 Length:548 Species:Homo sapiens
Sequence 2:NP_788674.1 Gene:CG9297 / 41688 FlyBaseID:FBgn0038181 Length:952 Species:Drosophila melanogaster


Alignment Length:408 Identity:107/408 - (26%)
Similarity:199/408 - (48%) Gaps:29/408 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    22 DARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKT 86
            :||.|....:.:.:...::::|...:.|||..|::.:..:....|.:..:||::|.:|.:|.||:
  Fly   522 NAREKATDNVAEIILRDIKRIYENAVKPLETLYKYRDLSNRHFSDPEIFSKPLILFMGPWSGGKS 586

Human    87 TFIRHLIEQDFP--GMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRRPFRKLNAFGNAFLNR 149
            :.:.:|.:.::.  .:|.|.||:...|..:|.|....|:.|..|..|  ..|..|..||.....|
  Fly   587 SILNYLTDNEYTPNSLRTGAEPSPAYFNILMWGNETEVLDGTQLAAD--YTFAGLQKFGQGLEER 649

Human   150 FMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEF 214
            ....::.:.:|:.::|::.||||...|| :||.:.|....:||.:|.|.|.|::|..|||:..|.
  Fly   650 LRGLKMKSKILEKVNIVEIPGILEVRKQ-VSRVFPFNDACQWFIDRADIIFLVYDPAKLDVGPET 713

Human   215 SEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIP 279
            ..::..||..|.:.|::|||||.::.::|:||.|||:|::..::::.:...:|..|.|:||....
  Fly   714 EAILDQLKGREYQTRIILNKADTVKPEELLRVQGALIWNISPLMSSAQPPLMYTTSLWTHPYQDG 778

Human   280 DNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARLAKV----HAYIISSLKKEMPN---VFG 337
            ...:|..|:|:...:|:    |.|..:::...|..||...|    ||.::........|   :||
  Fly   779 APARLLLAQERAFLRDL----RTAIDKRIEHKIASARRFAVRVRNHAKMVDCYLNTFNNHKTLFG 839

Human   338 KESKKKELVNNLGE------IYQKIEREHQISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTV 396
               .||.:.:::.:      ||:.:.....||..|.|.....::..:.....:|:    ||.||.
  Fly   840 ---NKKRIADDIIDHPQNYHIYEGLSTLTNISRYDLPDPEVYRDFFRLNPLYEFK----KLRDTC 897

Human   397 DDMLANDIARLMVMVRQE 414
            .......|.:|.:.:..|
  Fly   898 TYFRGCPITKLDLAIAYE 915

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EHD1NP_001269374.1 EHD_N 38..70 CDD:465295 6/31 (19%)
EHD 74..314 CDD:206740 72/241 (30%)
DUF5600 302..408 CDD:465667 24/118 (20%)
EH 452..545 CDD:197477
CG9297NP_788674.1 MSCRAMM_ClfA <93..367 CDD:468110
TSP3 repeat_long 167..205 CDD:275366
EHD_N 539..570 CDD:465295 6/30 (20%)
EHD 574..813 CDD:206740 74/245 (30%)
Blue background indicates that the domain is not in the aligned region.

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