DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BTNL3 and Btnl6

DIOPT Version :9

Sequence 1:	NP_932079.1	Gene:	BTNL3 / 10917	HGNCID:	1143	Length:	466	Species:	Homo sapiens
Sequence 2:	NP_109672.1	Gene:	Btnl6 / 624681	MGIID:	1932038	Length:	539	Species:	Mus musculus

Alignment Length:	494	Identity:	157/494 - (31%)
Similarity:	251/494 - (50%)	Gaps:	67/494 - (13%)

- Green bases have known domain annotations that are detailed below.

Human     3 FVLILVLSFYELVSGQWQVTGPGKFVQALVGEDAVFSCSLFPETSAEAM-EVRFFRNQFHAVVHL 66
            ||||.:||:  :.:.::||.||...:.|..|.:|:..||:.|..:.|.| |:|:||::|.|.|.:
Mouse    17 FVLIQLLSW--VTTKEFQVFGPSDPIVAAPGGEAILPCSVIPAMNVENMEELRWFRSRFSAAVLV 79

Human    67 YRDGEDWESKQMPQYRGRTEFVKDSIAGGRVSLRLKNITPSDIGLYGCWFSSQIYDEEATWELRV 131
            |||.|:.:.:|:|:|..||..||:....|..::|:.|:...|.|:|.|.|...::.|||..||:|
Mouse    80 YRDQEEQKREQLPEYSQRTSLVKEQFHQGTAAVRILNVQAPDSGIYICHFKQGVFYEEAILELKV 144

Human   132 AALGSLPLISIVGYVDGGIQLLCLSSGWFPQPTAKWKGPQGQDLSSDSRANA-DGYSLYDVEISI 195
            ||:||:|.:.|.|..|||:.::|::|||:|:|...||..:|:.|::....:: |...|:..|.|:
Mouse   145 AAMGSVPEVYIKGPEDGGVCVVCITSGWYPEPQVHWKDSRGEKLTASLEIHSEDAQGLFRTETSL 209

Human   196 IVQENA-GSILCSIHLAEQSHEVESKVLIGETFF-QPSPWRLASILLGLLCGALCGVVMGMIIVF 258
            :|:::: .::.||........|....:.:.|.|| :.|||:.|..:...:.|.|   |:|...:|
Mouse   210 VVRDSSVRNVTCSTFNPILGQEKAMAMFLPEPFFPKVSPWKPAFFVTLTMMGLL---VLGTSYLF 271

Human   259 FKSK----------GKIQ------AELD----------------------WRRKHGQAELRDARK 285
            .:.:          |.:|      ||.|                      ||:....|:.|..:.
Mouse   272 RRERSARLIVQELTGNLQRVEDNKAEEDTVRTIDALMVELAQRKAAYRAAWRKAQLYADWRKEQF 336

Human   286 HAVEVTLDPETAHPKLCVS-DLKTVTHRKAPQEVPHSEKRFTR-----KSVVASQGFQAGKHYWE 344
            .|...||||.:||..|.:| |..|||           .|.|||     ..|:..:|..:|::|||
Mouse   337 QAWTFTLDPASAHTNLAISQDRLTVT-----------RKDFTRCLEDLSCVLGIRGISSGRYYWE 390

Human   345 VDVGQNVG--WYVGVCRDDVDRGKNNVTLSPNNGYWVLRLTTEHLYFTFNPHFISLPPSTPPTRV 407
            |.:....|  |.:||||:.|.| ||....:|..|:|.:..:::..:...:....||.....|..|
Mouse   391 VKLTNIEGSKWILGVCREGVVR-KNFYFETPRKGFWTVGQSSKGHWAYIDSGRTSLSVRQAPKSV 454

Human   408 GVFLDYEGGTISFFNTNDQSLIYTLLTCQFEGLLRPYIQ 446
            |||:||..|.|||:|.:|.|.:::.....|.|.|.||.:
Mouse   455 GVFVDYTEGDISFYNMSDMSHMFSFPKASFSGTLFPYFR 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTNL3	NP_932079.1	Ig_MOG_like	33..132	CDD:319291	38/99 (38%)
BTNL3	NP_932079.1	SPRY_PRY_C-I_1	289..461	CDD:293968	57/166 (34%)
Btnl6	NP_109672.1	Ig	45..145	CDD:386229	38/99 (38%)
		Ig	150..232	CDD:386229	23/81 (28%)
		SPRY_PRY_C-I_1	341..503	CDD:293968	57/165 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG39342
OrthoDB	1	1.010	-	-		D175892at32523
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X198
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930