Protein Alignment BTNL3 and syg-1

DIOPT Version :9

• Sequence 1: NP_932079.1
• Gene: BTNL3 / 10917
• HGNCID: 1143
• Length: 466
• Species: Homo sapiens
• Sequence 2: NP_001123159.1
• Gene: syg-1 / 180555
• WormBaseID: WBGene00006365
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 106/545 - (19%)
• Similarity: 170/545 - (31%)
• Gaps: 194/545 - (35%)

Human     8 VLSFYELVSG---QWQVTGPGKFVQALVGEDAVFSCSLFPETSAEAMEVRFFRNQFHAVVHLYRD 69
            :|..::||:.   |.::....|...|.|||.|:.:|    ....:...|::.::.|..
 Worm     9 LLLLFQLVTCQQLQQRIVEAPKDTLAAVGETAILTC----RVEHQQGPVQWMKDDFGL------- 62

Human    70 GEDWESKQMP---QYRGRTEFVKDSIAGGRVSLRLKNITPSDIGLYGCWFSSQ-----IYDEEAT 126
            |.| ..|.:|   :||     :..|.|.|..:|.:.|:|..|...:.|..|..     :...:|
 Worm    63 GTD-RDKPLPGNKRYR-----MVGSAANGEYNLEISNVTLFDDDDFACQISESDHAKAVVSSKA- 120

Human   127 WELRVAALGSLPLI-----SIVGYVDGGIQLLCLSSGWFPQPTAKW------------------- 167
             :|.|....:.|.|     |:.......|...|||....|.||..|
 Worm   121 -KLTVLVRPTPPKIVKSHHSLKAIAGDPITQSCLSRKGKPPPTIGWAIASDEHGKHIVSWLGESR 184

Human   168 ----------------------KGPQGQDLSSDSRANADGYSLY-----------DVEISIIVQE 199
                                  :..|.::..::||.::..||:.           |.:..|.:.:
 Worm   185 SKFGGIHAKPEISQETVIAHVNETTQVEEGGNNSREDSSIYSIMSNLSFIPRPEDDHKYLICISQ 249

Human   200 N--------AGSILCSIHLAEQSH-EVESKVLIGETFFQPSPWRLASILLGLLCGALCGVVMGMI 255
            :        ..|:..|:..|.|.: .|.||:.:.|.         .|.||.      |.|
 Worm   250 HMTFPNKIEVDSVKLSLRYAPQINLTVASKLPLREN---------GSALLA------CNV----- 294

Human   256 IVFFKSKGKIQAELDWRRKHGQAELRDARKHAVEVTLDPETAHPKLCVSDLKTVTHRK-----AP 315
                .:|.....::.|.:  |..:||:...     ||..||         ||...|.:     |.
 Worm   295 ----NAKPLDNVKISWYK--GNQKLRETGD-----TLTFET---------LKMEDHNRDIFCEAT 339

Human   316 QEVPHSEKRFTRKSVVASQGFQA----GKHYWEVDVGQN--------------VGWYVGVCRDDV 362
            .|:     ..||.|:..:..|.|    .....||:.|.|              :.|..|...:.:
 Worm   340 NEI-----GTTRGSIKLNVAFGARIMSTSQDKEVNEGDNAFFHCATLANPAPAIFWTRGDSDEII 399

Human   363 DRGKNNVTLSP----NNGYWVLRLTTEHLYFTFNPHFISLPPSTPPT-----RVGVFLDYEGGTI 418
            ..|: |:||..    ..|.:....|.|........|::.:  ..|||     .|...||..
 Worm   400 GHGE-NLTLENVRTWQQGNYNCTATVEGFRKQILSHYLHI--RGPPTVSMKDEVSASLDEA---- 457

Human   419 SFFNTNDQSLIYTLLTCQFEGLLRP 443
                        |.:.|:..|  ||
 Worm   458 ------------TEIICEISG--RP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BTNL3	NP_932079.1	Ig_MOG_like	33..132	CDD:319291	23/106 (22%)
		SPRY_PRY_C-I_1	289..461	CDD:293968	39/187 (21%)
syg-1	NP_001123159.1	I-set	24..124	CDD:254352	26/118 (22%)
		Ig	30..124	CDD:299845	26/112 (23%)
		Ig	<151..265	CDD:299845	15/113 (13%)
		Ig_2	276..353	CDD:290606	26/121 (21%)
		IG_like	283..353	CDD:214653	23/114 (20%)
		IG_like	363..427	CDD:214653	13/64 (20%)
		Ig_2	368..438	CDD:290606	13/70 (19%)
		Ig	440..528	CDD:299845	11/47 (23%)
		IG_like	450..535	CDD:214653	8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910