DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTNL3 and ncam-1

DIOPT Version :9

Sequence 1:	NP_932079.1	Gene:	BTNL3 / 10917	HGNCID:	1143	Length:	466	Species:	Homo sapiens
Sequence 2:	NP_741709.1	Gene:	ncam-1 / 180418	WormBaseID:	WBGene00017184	Length:	955	Species:	Caenorhabditis elegans

Alignment Length:	121	Identity:	28/121 - (23%)
Similarity:	48/121 - (39%)	Gaps:	23/121 - (19%)

- Green bases have known domain annotations that are detailed below.

Human   108 DIGLYGCWFSSQIYDEEATWELRVAALGSLPLISIVGYVDGG-------IQLLCLSSGWFPQPTA 165
            |.|:|.|  ::..|....|..:.|... :.|.|::....:|.       |:|.|.:.| .|:||.
Worm   214 DDGIYNC--NAAQYSSFETLSVNVTGY-ARPTITVFDVPNGNRGIEGHTIELKCGAVG-KPKPTY 274

Human   166 KWKGPQGQDLSSDSRANADGYSLYDVEISIIV-----QENAGSILCSIHLAEQSHE 216
            ||       ...|..........::||..:::     .|:||:..|..:....|:|
Worm   275 KW-------FFEDDEVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNE 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTNL3	NP_932079.1	Ig_MOG_like	33..132	CDD:319291	6/23 (26%)
BTNL3	NP_932079.1	SPRY_PRY_C-I_1	289..461	CDD:293968
ncam-1	NP_741709.1	IG	64..142	CDD:214652
		Ig	69..140	CDD:143165
		IG_like	153..236	CDD:214653	6/23 (26%)
		Ig	160..222	CDD:299845	4/9 (44%)
		IG_like	256..330	CDD:214653	18/76 (24%)
		IGc2	256..320	CDD:197706	16/71 (23%)
		IG_like	<445..499	CDD:214653
		Ig	<445..498	CDD:143165
		IG_like	520..596	CDD:214653
		IGc2	520..587	CDD:197706
		FN3	<652..701	CDD:238020
		FN3	<817..873	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910