Protein Alignment DHRS4 and CG31546

DIOPT Version :9

• Sequence 1: NP_066284.2
• Gene: DHRS4 / 10901
• HGNCID: 16985
• Length: 278
• Species: Homo sapiens
• Sequence 2: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 80/262 - (30%)
• Similarity: 139/262 - (53%)
• Gaps: 12/262 - (4%)

Human    19 MASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQN---VDQAVATLQGEG 80
            |.|.|....| .:.||.|:|.:..|||.|.|...::.||.:.:..|:::.   |.:....:..|.
  Fly     1 MGSKGKAGLD-FSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEP 64

Human    81 LSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAP 145
            ..:.|.:....:.|...|  .|..:..|.:|:||:.|.:.| .|::.......:...::.||::.
  Fly    65 YGIAGDLLKPPEIECIAR--KTTERYEGKLDVLVNGAGIMP-TGTLQSTELACFTHVMEANVRSG 126

Human   146 ALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
            ..:||.::|:: .:..||:|.|||:......|....||:||.|:...|::||::|.|:.:|||.:
  Fly   127 FYLTKLLLPQL-LQCKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAV 190

Human   211 APGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVG 271
            .||:|:|:..:...||::..    |..|:|..:.|:|||::.|..:.||.||.||::||.|:.|.
  Fly   191 NPGVIRTNLQKAGGMDEQSYAEFLEHSKKTHALGRIGEPKEVAAAICFLASELASFVTGVTLPVD 255

Human   272 GG 273
            ||
  Fly   256 GG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS4	NP_066284.2	CR_SDR_c	23..278	CDD:187641	78/258 (30%)
		fabG	30..273	CDD:235975	74/249 (30%)
		Microbody targeting signal	276..278
CG31546	NP_730973.1	fabG	9..257	CDD:235975	75/252 (30%)
		NADB_Rossmann	11..261	CDD:304358	76/251 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740