Protein Alignment CPSF4 and YTH1

DIOPT Version :9

• Sequence 1: XP_011514057.1
• Gene: CPSF4 / 10898
• HGNCID: 2327
• Length: 274
• Species: Homo sapiens
• Sequence 2: NP_015432.1
• Gene: YTH1 / 856222
• SGDID: S000006311
• Length: 208
• Species: Saccharomyces cerevisiae
• Alignment Length: 146
• Identity: 67/146 - (45%)
• Similarity: 92/146 - (63%)
• Gaps: 13/146 - (8%)

Human    40 VCEFFLK----AACGKGGMCPFRHISG--EKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYF 98
            :|||:..    .:|.:|.:||.:|:..  :..:||:|||||||||.||||:||||::.|||||.|
Yeast    33 ICEFYNSREGPKSCPRGPLCPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPECVF 97

Human    99 YSKFGECS-NKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEG-PS 161
            :||.|.|: :.:|.:|||||.|||..|..|:.|||..|..|..||.::|.|..|:.||||.| ..
Yeast    98 FSKNGYCTQSPDCQYLHIDPASKIPKCENYEMGFCPLGSSCPRRHIKKVFCQRYMTGFCPLGKDE 162

Human   162 CKFMQLLVTSPRFELP 177
            |.     :..|:|.:|
Yeast   163 CD-----MEHPQFIIP 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPSF4	XP_011514057.1	YTH1	<25..>161	CDD:227416	63/128 (49%)
		COG5222	<231..>263	CDD:227547
YTH1	NP_015432.1	YTH1	2..208	CDD:227416	67/146 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I1373
Isobase	1	0.950	-	0	Normalized mean entropy	S731
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002750
OrthoInspector	1	1.000	-	-		otm52706
orthoMCL	1	0.900	-	-		OOG6_103251
Panther	1	1.100	-	-	LDO	PTHR23102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2013
SonicParanoid	1	1.000	-	-		X2133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.800