Protein Alignment CPSF4 and cpsf-4

DIOPT Version :9

• Sequence 1: XP_011514057.1
• Gene: CPSF4 / 10898
• HGNCID: 2327
• Length: 274
• Species: Homo sapiens
• Sequence 2: NP_001023126.1
• Gene: cpsf-4 / 178151
• WormBaseID: WBGene00044329
• Length: 302
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 139/299 - (46%)
• Similarity: 170/299 - (56%)
• Gaps: 66/299 - (22%)

Human     1 MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKT 65
            |.::::::.....|:|.|:..|.|.:..||..:|:||.|||.......|..|..||.|||.|||.
 Worm    15 MTDLVSNITAPMTDVEEALFNQRGMKEAPFRDLDRSGKAVCRKNKLKMCPFGPTCPLRHIDGEKA 79

Human    66 VVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRG 130
            ||||||||||||||||||||||||:||||||:|:||:..|||:||||.|||||:|:|||||||||
 Worm    80 VVCKHWLRGLCKKGDQCEFLHEYDLTKMPECFFFSKYSACSNRECPFRHIDPETKMKDCPWYDRG 144

Human   131 FCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMQLLVTSPRFELPM----------------- 178
            ||:|||.|:|||.||.:|.|||.|||.:||.|::     ..|.|.||.
 Worm   145 FCRHGPYCKHRHRRRAVCPNYLAGFCLQGPDCQY-----AHPSFGLPSFENIAVSHAKPTYSQAI 204

Human   179 ----------GTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQ 233
                      ..|..|.||.||    :|:.:...:...|||        |:::.
 Worm   205 TCHNCHERGHKATTCPHLPGQT----RQNQDHHHRVDLSLI--------PDKKN----------- 246

Human   234 NSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLS 272
                       |..||||||||||||||||.||.|||||
 Worm   247 -----------LSDVTCYKCGEKGHYANRCHKGALAFLS 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPSF4	XP_011514057.1	YTH1	<25..>161	CDD:227416	92/135 (68%)
		COG5222	<231..>263	CDD:227547	15/31 (48%)
cpsf-4	NP_001023126.1	YTH1	<66..187	CDD:227416	88/125 (70%)
		ZnF_C3H1	77..102	CDD:214632	23/24 (96%)
		ZnF_C3H1	133..158	CDD:214632	19/24 (79%)
		ZnF_C3H1	157..181	CDD:214632	12/28 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5084
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38216
Inparanoid	1	1.050	287	1.000	Inparanoid score	I1948
Isobase	1	0.950	-	0	Normalized mean entropy	S731
OMA	1	1.010	-	-		QHG49855
OrthoDB	1	1.010	-	-		D1472764at2759
OrthoFinder	1	1.000	-	-		FOG0002750
OrthoInspector	1	1.000	-	-		oto23378
orthoMCL	1	0.900	-	-		OOG6_103251
Panther	1	1.100	-	-	LDO	PTHR23102
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2013
SonicParanoid	1	1.000	-	-		X2133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.820