Protein Alignment PPARGC1A and Ppargc1a

DIOPT Version :10

• Sequence 1: NP_001317680.1
• Gene: PPARGC1A / 10891
• HGNCID: 9237
• Length: 803
• Species: Homo sapiens
• Sequence 2: XP_036020787.1
• Gene: Ppargc1a / 19017
• MGIID: 1342774
• Length: 819
• Species: Mus musculus
• Alignment Length: 790
• Identity: 741/790 - (93%)
• Similarity: 765/790 - (96%)
• Gaps: 4/790 - (0%)

Human    18 REAGW---QCAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPS 79
            :::.|   :|||||||||||||||||||||||||||||||||||||||||||||||||||||||:
Mouse     8 QDSVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPA 72

Human    80 NIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAE 144
            |||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||
Mouse    73 NIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGAVTTDNEASPSSMPDGTPPPQEAE 137

Human   145 EPSLLKKLLLAPANTQLSYNECSGLSTQNH-ANHNHRIRTNPAIVKTENSWSNKAKSICQQQKPQ 208
            |||||||||||||||||||||||||||||| |||.||||||||||||||||||||||||||||||
Mouse   138 EPSLLKKLLLAPANTQLSYNECSGLSTQNHAANHTHRIRTNPAIVKTENSWSNKAKSICQQQKPQ 202

Human   209 RRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCTSKKKSHTQSQSQHLQAKPTTLSLPLTPESPN 273
            |||||||||||||||||||||||||||||||||.||||||||.||||.|||||||||||||||||
Mouse   203 RRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCASKKKSHTQPQSQHAQAKPTTLSLPLTPESPN 267

Human   274 DPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRY 338
            ||||||||||||||||||||||||||||||||||||||||||:||||||.|||||||||:|:.||
Mouse   268 DPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFKASPKLKPSCKTVVPPPTKRARY 332

Human   339 SESSGTQGNNSTKKGPEQSELYAQLSKSSVLTGGHEERKTKRPSLRLFGDHDYCQSINSKTEILI 403
            ||.|||||::|||||||||||||||||||.|:.|||||||||||||||||||||||:||||:|||
Mouse   333 SECSGTQGSHSTKKGPEQSELYAQLSKSSGLSRGHEERKTKRPSLRLFGDHDYCQSLNSKTDILI 397

Human   404 NISQELQDSRQLENKDVSSDWQGQICSSTDSDQCYLRETLEASKQVSPCSTRKQLQDQEIRAELN 468
            ||||||||||||:.||.|.||||.|||||||.|||||||||||||||||||||||||||||||||
Mouse   398 NISQELQDSRQLDFKDASCDWQGHICSSTDSGQCYLRETLEASKQVSPCSTRKQLQDQEIRAELN 462

Human   469 KHFGHPSQAVFDDEADKTGELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLSYPWDGT 533
            ||||||.||||||::|||.||||.|||||||||||:|||||||||||||||||||||||||||||
Mouse   463 KHFGHPCQAVFDDKSDKTSELRDGDFSNEQFSKLPVFINSGLAMDGLFDDSEDESDKLSYPWDGT 527

Human   534 QSYSLFNVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGS 598
            |.||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   528 QPYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGS 592

Human   599 RSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRE 663
            |||||||||||||||||||||||||||||||||||||||||||||.|:||||||:|||:|:||||
Mouse   593 RSSSRSCYYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEAYEHERLKRDEYRKEHEKRE 657

Human   664 SERAKQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYR 728
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   658 SERAKQRERQKQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYR 722

Human   729 YTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSL 793
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Mouse   723 YTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDTNSDDFDPASTKSKYDSLDFDSL 787

Human   794 LKEAQRSLRR 803
            ||||||||||
Mouse   788 LKEAQRSLRR 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPARGC1A	NP_001317680.1	Complexin_NTD	641..676	CDD:459253	28/34 (82%)
		RRM_PPARGC1A	680..770	CDD:410034	89/89 (100%)
Ppargc1a	XP_036020787.1	RRM_PPARGC1A	674..764	CDD:410034	89/89 (100%)