Protein Alignment RAB10 and Rab7

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_524472.1
• Gene: Rab7 / 42841
• FlyBaseID: FBgn0015795
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 170
• Identity: 64/170 - (37%)
• Similarity: 105/170 - (61%)
• Gaps: 10/170 - (5%)

Human     9 LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHT 73
            |.|::::|||.||||.::.::.:..|:..:.:|||.||..|.|.:..:.:.:|||||||||||.:
  Fly     8 LLKVIILGDSSVGKTSLMNQYVNKRFSNQYKATIGADFCTKEVVVNDRVVTMQIWDTAGQERFQS 72

Human    74 ITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVER-------MLLGNKCDMDDKRV 131
            :..::||||...:||||:|...||:|:..|.   ||...:...|       ::||||.|:|:::|
  Fly    73 LGVAFYRGADCCVLVYDVTAPNSFKNLDSWR---DEFLIQASPRDPDHFPFVVLGNKVDLDNRQV 134

Human   132 VPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDIL 171
            ..:...:....::.|.::|||||..||:|.||..:|::.|
  Fly   135 STRRAQQWCQSKNDIPYYETSAKEGINVEMAFQVIAKNAL 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	64/170 (38%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		9/16 (56%)
Rab7	NP_524472.1	Rab7	9..179	CDD:206655	63/169 (37%)