Protein Alignment RAB10 and Rab1

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_732610.1
• Gene: Rab1 / 42524
• FlyBaseID: FBgn0285937
• Length: 205
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 110/200 - (55%)
• Similarity: 143/200 - (71%)
• Gaps: 7/200 - (3%)

Human     6 YDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
            ||.||||||||||||||:|:|.||:||.:..::|||||:||||:|:||.||.|||||||||||||
  Fly     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72

Human    71 FHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKG 135
            |.|||:||||||.||::|||.|:.:||.|:.:||..|:.:|.|:|.::|:|||.|:..|:||...
  Fly    73 FRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHT 137

Human   136 KGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEP-----NSENVDISSGGGVTGW 195
            ...:.|.:.||.|.|||||:..|:|:||:|:|.:|  |..|..|     |:..|.|..|..|...
  Fly   138 TAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEI--KNRVGPPSSATDNASKVKIDQGRPVENT 200

Human   196 KSKCC 200
            ||.||
  Fly   201 KSGCC 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	97/165 (59%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		14/16 (88%)
Rab1	NP_732610.1	Rab1_Ypt1	10..175	CDD:206661	97/166 (58%)