Protein Alignment RAB10 and Rab11

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 208
• Identity: 89/208 - (42%)
• Similarity: 134/208 - (64%)
• Gaps: 15/208 - (7%)

Human     6 YDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQER 70
            ||.|||::|||||||||:.:|.||:.:.||....||||::|..:::|:.||.||.||||||||||
  Fly     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQER 72

Human    71 FHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVPKG 135
            :..||::|||||:|.:|||||....::||:.:|||.:.:||::::..||:|||.|:...|.||..
  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTD 137

Human   136 KGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILR---KTPVKEP---------NSENVDISS 188
            :.:..|..:|:.|.||||..:.|:|.||..:..:|.|   :..:::|         |.|.:|:..
  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEPIDVKP 202

Human   189 GGGVTG-WKSKCC 200
              .||. .:.:||
  Fly   203 --TVTADVRKQCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	80/168 (48%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		11/16 (69%)
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	78/163 (48%)