Protein Alignment RAB10 and Rab23

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_649574.1
• Gene: Rab23 / 40701
• FlyBaseID: FBgn0037364
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 167
• Identity: 58/167 - (34%)
• Similarity: 98/167 - (58%)
• Gaps: 1/167 - (0%)

Human     1 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDT 65
            |.:...:|..|::::|:.||||:.::.|:....|...:..|||:||..:.:|:.|:.:::.:|||
  Fly    29 MREDDIELAIKVVIVGNGGVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIEIDGEDVRIMLWDT 93

Human    66 AGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKR 130
            ||||.|..||.:|||||...:||:..|:..||:.|..|.|.::...|| :..:::.||.|:.::.
  Fly    94 AGQEEFDCITKAYYRGAQASVLVFSTTDRASFDAIKDWKRKVENECNE-IPTVIVQNKIDLIEQA 157

Human   131 VVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLA 167
            ||...:.|.:|:....|...||.|.:||:...|..||
  Fly   158 VVTADEVETLAKLLNCRLIRTSVKEDINVASVFRYLA 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	57/161 (35%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		11/16 (69%)
Rab23	NP_649574.1	Rab23_like	50..197	CDD:133306	51/146 (35%)