DRSC/TRiP Functional Genomics Resources

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Protein Alignment RAB10 and Rab4

DIOPT Version :10

Sequence 1:NP_057215.3 Gene:RAB10 / 10890 HGNCID:9759 Length:200 Species:Homo sapiens
Sequence 2:NP_523777.1 Gene:Rab4 / 36992 FlyBaseID:FBgn0016701 Length:213 Species:Drosophila melanogaster


Alignment Length:176 Identity:34/176 - (19%)
Similarity:52/176 - (29%) Gaps:65/176 - (36%)


- Green bases have known domain annotations that are detailed below.


Human    34 GRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQ-------------NPCAVACHGDPGNF 85
            |:..|.:.|.:.| :.|      ..|..::|....|||             ||.....|.:....
  Fly   208 GKVVVRFPPEASG-YLH------IGHAKAALLNQYYQQAFQGKLIMRFDDTNPAKENVHFEQVIL 265

Human    86 YGYDPLQRQSLFGAQDPDLV----QYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAGRR 146
            ...:.||.:       |||.    ||.|..|.....|.:|.:.......|.|             
  Fly   266 EDLEMLQIK-------PDLFTHTSQYFDLMLDYCVRLLKEGKAYVDDTEPEQ------------- 310

Human   147 RGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIW 192
                         ::||        |:.|:|..:.....||.:.:|
  Fly   311 -------------MKKE--------REERVESKNRSNTPERNLAMW 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RAB10NP_057215.3 Rab8_Rab10_Rab13_like 7..173 CDD:206659 28/155 (18%)
Switch 1. /evidence=ECO:0000250|UniProtKB:P62820 32..46 3/11 (27%)
Switch 2. /evidence=ECO:0000250|UniProtKB:P62820 64..81 7/29 (24%)
Rab4NP_523777.1 Rab4 9..169 CDD:206696
Blue background indicates that the domain is not in the aligned region.

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