Protein Alignment RAB10 and Rab9

DIOPT Version :10

• Sequence 1: NP_057215.3
• Gene: RAB10 / 10890
• HGNCID: 9759
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_609966.1
• Gene: Rab9 / 35221
• FlyBaseID: FBgn0032782
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 213
• Identity: 65/213 - (30%)
• Similarity: 108/213 - (50%)
• Gaps: 33/213 - (15%)

Human     9 LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQERFHT 73
            |.|::::||.||||:.:|.||..:.:......|||::|..|.:.:.|::..||||||||||||..
  Fly    12 LLKVVILGDGGVGKSALLTRFVANRYEENNFHTIGVEFMNKDIVVDGERYTLQIWDTAGQERFRA 76

Human    74 ITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVER---MLLGNKCDMD-DKRVVPK 134
            :.|.:|||:...:|.|.:.:..|.:.:..|......:|:.|.::   :::|||.|:. .||.|..
  Fly    77 LRTPFYRGSDICLLCYALDDRDSLKGLGVWRNEFLNYADVDQDKFPFIVVGNKNDIPAQKRQVSS 141

Human   135 GKGEQIAREHGIR-FFETSAKANINIEKAFL----------TLAEDILRKTPVKEPNSENVDIS- 187
            ...:|...|..:. ..|||:||..|:..||:          .:||..||:      :.:.:|::
  Fly   142 DAVQQWCAEQKVACHIETSSKAATNVTDAFVLGLRQWRHMECVAEAELRQ------HGDTIDLTR 200

Human   188 -----------SGGGVTG 194
                       :|||..|
  Fly   201 PIRLVQRRICCTGGGGGG 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB10	NP_057215.3	Rab8_Rab10_Rab13_like	7..173	CDD:206659	59/178 (33%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	32..46		3/13 (23%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	64..81		10/16 (63%)
Rab9	NP_609966.1	Rab9	8..178	CDD:206697	56/165 (34%)